What Are The Side Effects Of Tysabri?
There are a number of monoclonal antibodies that can be used
Detailed Answer:
Thanks for asking on HealthcareMagic.
I am sorry to know about your son. I have gone through the details of your concern. Multiple sclerosis (MS) is an autoimmune disease in which autoreactive T cells cross the blood-brain barrier and attack the myelin sheath leading to a cascade of inflammation. The result is demyelination, acute axonal transection, gliosis and subsequent axonal degeneration. Therapeutic monoclonal antibodies are potent new tools for a molecular targeted approach to modify the course of multiple sclerosis (MS). Besides natalizumab, three other monoclonal antibodies viz alemtuzumab, rituximab and daclizumab have been used for treatment of MS. Anti-TNFα antibodies (infliximab, adalimumab, and certolizumab pegol) can also be used. You can discuss with your doctor about the feasibility of the use of these but I doubt that the adverse effect profile would not be quite different.
The following links might be useful for you:
http://www.yyyyy.nlm.nih.gov/pmc/articles/PMC0000/
http://www.yyyyyyyy.com/y/572411yyyyyyyyyyyyyyy
I understand your concerns but let me assure you that Tysabri (natalizumab) seems to be reasonably good with a favorable adverse effect profile and you might be overanxious about the use of this tool. Other choices might not be wiser.
Regards