Brief Answer: Detail Follows Detailed Answer: Dear Friend. Welcome to HCM. I am Dr Anshul Varshney. I have read your query in detail. I understand your concern. As such there is a long list of side effects of every drug but everyone doesn't experiences all side effects. I will still mention few important considerations while you are on these drugs. Supermet XL can slow down your heart rate and can cause low blood pressure. You should check that your pulse rate doesn't fall below 60 beats per minute. Enam is a good drug but should be used cautiously in patient's with deranged kidney functions. Currently your Serum pottasium is normal. But you should keep a watch on it as it can cause rise in Serum potassium and its toxicity. Now your concern about your serum creatinine. Hypertensive nephropathy is a common complication of hypertension. As such there are no drugs available to reduce your creatinine levels. But a good control of blood pressure can reduce rate of it's progression and even it may come to normal. So control your blood pressure and diabetes if you have that too. Also I advice : 1. Renal artery Doppler. 2. 24 hour Urine for Albumin. 3. Fundus examination. I hope you find this information helpful. If you have a further query you may please ask me. Stay Healthy.

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