Hello,
Thank you for your query,
Each medicine mentioned by you are used to relieve symptoms of Parkinson’s disease and has many benefits but also and side effects. Their benefits are: decrease tremors, stiffness and impaired movement.
Amantrel side effects: dizziness, headaches, sleep disturbances, blurred vision, nausea, constipation.
Pramipexole side effects: visual abnormalities, decreased libido, insomnia, dizziness, nausea, malaise,
Rasagiline side effects: loss of hair, loss of appetite, gastrointestinal disturbances ( nausea, vomiting, diarrhea , constipation) headache, dizziness, decrease libido.
I believe that you are aware that a physician needs to be consulted before this medication is started for correct combination and dosage.

If you have additional queries, don’t hesitate to ask.

Best Regards,


Dr.Mihail

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Hello,
Thanks for coming back,

The mainstay of treatment of bradykinesia is a drug called levo dopa. The medications that you have mentioned are used primarily in early stages of Parkinson's and would provide only some relief in treating bradykinesia, rigidity and tremor. The treatment and dose again would vary from person to person.

If you have additional queries ,don’t hesitate to ask.

Best Regards,


Dr.Mihail

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Hello,
Thanks for writing back.
All these 3 drugs help in the early stages of Parkinson's. So each of them is active against tremor, bradykinesia and rigidity, although to a variable extent. These are motor problems and these drugs would be effective against all these motor disturbances seen in parkinson's.
Reducing the dose can potentially worsen the symptoms. However, the dosage needs to be decided by balancing both effects and side effects. That balancing exercise needs to be done by a neurologist with whom you're in touch.
If you have additional queries, don’t hesitate to ask.
Best Regards,
Dr.Mihail

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