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What Are The Chances Of HIV After Intercourse With Negative 4th Generation Test?

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Posted on Mon, 23 Jun 2014
Question: I had a girlfriend who test right before had me. She made a 4th generation exam as routine because she only had a boyfriend for about 3 years who tested to donate blood (negative too). After that she only had me about 5 months after. On the week of 14 February we had an unprotected relation. At 11 weeks i've made 4th generation with p24 ant search negative. At 12 weeks rapid test negative. At 13 weeks rapid test negative. At 14 weeks another 4th generation exam and rapid test negative. I've to say that she made at 13 weeks as i begged her a rapid test (came negative). Should i be worried?

Thank you
doctor
Answered by Dr. Sankaranantham Murugan (3 hours later)
Brief Answer:
You are HIV free, no further test is need.

Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.

You are quite safe and there is nothing to worry.
4th generation test is highly reliable and conclusive. As P24 antigen part of this 4th generation test is conclusive after 4 weeks of high risk activity. But you had this test after 14 weeks and it came negative. Moreover rapid test and antibody part also becomes conclusive after 12 weeks. This was also negative for you after 13 weeks and 14 weeks. Moreover your sex partner also was negative for HIV after 12 weeks. So there is no chance for HIV infection for you both at present and It is conclusive both of you free from HIV.
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (2 days later)
Doctor,

Just one last question, there is no possibility of result changing?
doctor
Answered by Dr. Sankaranantham Murugan (1 hour later)
Brief Answer:
Normal immunocompetent person result is conclusive

Detailed Answer:
Hi,
Welcome back.

Not at all. So only, I put it as a conclusive one. If you are on any immunosuppressive drugs, or on any abusive drugs or if you have any congenital immunosuppressive condition, then there may be a delay in appearing of HIV antibodies and the rapid test for HIV also might be delayed up to 6 months to manifest. But in this situation also P24 part of the test in this 4th generation would not get affected. So you are HIV free and need not worry at all.
Dr S.Murugan
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3110 Questions

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What Are The Chances Of HIV After Intercourse With Negative 4th Generation Test?

Brief Answer: You are HIV free, no further test is need. Detailed Answer: Hi, Welcome to HCM. Thanks for posting your query. You are quite safe and there is nothing to worry. 4th generation test is highly reliable and conclusive. As P24 antigen part of this 4th generation test is conclusive after 4 weeks of high risk activity. But you had this test after 14 weeks and it came negative. Moreover rapid test and antibody part also becomes conclusive after 12 weeks. This was also negative for you after 13 weeks and 14 weeks. Moreover your sex partner also was negative for HIV after 12 weeks. So there is no chance for HIV infection for you both at present and It is conclusive both of you free from HIV. Dr S.Murugan