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Undergoing radiotherapy for lung cancer. Brain MRI shows microvascular gliosis. Need explanation

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my wife is undergoing radiation therapy for lung cancer. her oncologist ordered a brain mri as a precaution. one of the results from the report referred to microvascular gliosis. please explain a general overview. is it a result of radiation? is it usually permanent?
Posted Fri, 12 Apr 2013 in Lung Cancer
 
 
Answered by Dr. Hari Charan Perigela 58 minutes later
Hi
Microvascular disease is a process through which the very small branches of arteries become damaged.Gliosis is excess of astroglia in damaged areas of central nervous system.
It is not due to radiation therapy of lung cancer.
It is seen in many conditions like Migraine,high blood pressure,hardening of small arteries by atherosclerotic disease or sometimes in old or burned out multiple sclerosis.
As your wife's age is 62,it could be due to atherosclerosis.
So,these findings are incidental.
Nothing to worry.
Wish her good health and speedy recovery
Regards
Above answer was peer-reviewed by
 
Follow-up: Undergoing radiotherapy for lung cancer. Brain MRI shows microvascular gliosis. Need explanation 11 minutes later
thank you, i will pass on your answer. Also, the finding showed "associated parenchymal loss on the right characteristic of a chronic subcortical infarction." 3-4 in number. also not associated with radiation and "normal" for her age? also, there was no evidence of metastatic disease. Should we not be concerned with brain function and focus on the lung cancer? radiation is done and one more chemo treatment left.
 
 
Answered by Dr. Hari Charan Perigela 1 hour later
Hi
As the term 'chronic' suggests long duration,the associated parenchymal loss is also due to her age.
If her levels of consciouness,behaviour,movements of all the limbs are normal,you should not worry about brain function.
As metastasis to her brain has been excluded,please concentrate on the lung cancer treatment.
As Chemo treatment is planned,i wish her good health and speedy recovery
Regards
Above answer was peer-reviewed by
 
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