Hello and welcome to Healthcare Magic. Thanks for your query.

It is likely that these symptoms could be due to the side effects of Vyvanse or due to an anaphylactic (allergic) reaction to the medication.

Vyvanse (lisdexamfetamine), can have side effects of causing vasoconstriction (narrowing of the arteries), congestion of blood vessels and even an abnormal increase in blood pressure; and these effects could be the cause of her symptoms. Sometimes, there can be a severe allergic reaction which can also result in such symptoms.

I would advise you to take her to the ER as early as possible, for further evaluation and management. A discolouration of the hands may indicate poor blood supply and so, it is important to seek urgent medical help.

Regards,
Dr. Jonas Sundarakumar
Consultant Psychiatrist

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It is quite possible to have different responses to a drug at different times; blood levels of the drug can vary according to the rate of absorption or there can even be a possible drug interaction with some other substance, resulting in these side effects. Especially, if she has taken any other medication or alcohol or other substances recently, then it is likely that these symptoms could be due to an drug interaction.

However, the important thing is that her symptoms appear significant enough to warrant urgent medical attention. So, please have her examined by a doctor as soon as possible.

Regards,
Dr. Jonas Sundarakumar
Consultant Psychiatrist

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