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Tested Reactive For Hep B Core And Non Reactive For Hep C Antibody. Can I Donate Blood?

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Posted on Sat, 16 Mar 2013
Question: My fiance donated blood and tested 'Reactive' for Hepatitis B Core Antibody (HBc) but not for Surface Antigen Hepatitis B(HBsAg) and Non Reactive for Hepatitis C Antibody. He told me that he contracted it at birth and that he can no longer donate blood because it has come up reactive twice for HBc. The first time he donated was somewhere around a year ago. What is the option now?
doctor
Answered by Dr. Dr. Rahul Kumar (31 minutes later)
Hello,
Thanks for writing to us,
Hepatitis B Core Antibody (HBc), appears at the onset of symptoms in acute hepatitis B and persists for life. The presence of anti-HBc indicates previous or ongoing infection with hepatitis B virus.

The presence of HBsAg indicates that the person is infectious.

Your fiance is HBc positive and HBsAg negative.

To clear the picture, he needs to get Anti HBs done.

Hepatitis B surface antibody (anti-HBs),positivity, indicates recovery and immunity from hepatitis B virus infection. Anti-HBs also develop in a person who has been successfully vaccinated against hepatitis B.

If anti-HBs is positive,it means he has acquired immunity, is not infective and can donate blood.

Hope I answered your query,

Feel free to ask any further doubts.

Wishing your fiance a good health.

Thank you

Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
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Follow up: Dr. Dr. Rahul Kumar (16 hours later)
So why is the blood bank saying he cannot donate blood if he tells me that he's been vaccinated?
According to blood bank he tested positive twice for HBc. How can we figure out when the initial infection occurred and what should be done to prevent it from being spread or future health problems for him?
Luckily I have been vaccinated less than 20 years ago so I should be ok, correct? But what are future precautions I should take or risk of getting it from him if he in fact is infectious and I end up living with him?
You said HBc is present at the onset of symptoms, does that mean he recently became infected?
What is there to do now?
He's not very honest regarding his history so I am rightfully concerned and just need to hear facts and the truth regarding this disease.
I have not perceived any symptoms in him so I believe it's asymptomatic.
How can I get answers?
We've been together going on 3 years now and known each other for 7 years, yet this is just now surfacing. Please give me as much details as you can so that I may be better informed. Thank you so much.
doctor
Answered by Dr. Dr. Rahul Kumar (2 hours later)
Hello,
thanks for follow up,
I understand your concern, thats why I said get his anti-HBs done, if this is also positive surely he is vaccinated.
Be sure for one thing he is not infective now.
Its true that anti HBc, occurs in early infection. but it must be associated with surface antigen too.
Here I am sharing with you a link of the centre of disease control, you will get the entire detail in a tabular form, very easy to understand.
WWW.WWWW.WW
Hope this helps. let me know your doubts.

Thank you
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Dr. Rahul Kumar

Dermatologist

Practicing since :2010

Answered : 6634 Questions

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Tested Reactive For Hep B Core And Non Reactive For Hep C Antibody. Can I Donate Blood?

Hello,
Thanks for writing to us,
Hepatitis B Core Antibody (HBc), appears at the onset of symptoms in acute hepatitis B and persists for life. The presence of anti-HBc indicates previous or ongoing infection with hepatitis B virus.

The presence of HBsAg indicates that the person is infectious.

Your fiance is HBc positive and HBsAg negative.

To clear the picture, he needs to get Anti HBs done.

Hepatitis B surface antibody (anti-HBs),positivity, indicates recovery and immunity from hepatitis B virus infection. Anti-HBs also develop in a person who has been successfully vaccinated against hepatitis B.

If anti-HBs is positive,it means he has acquired immunity, is not infective and can donate blood.

Hope I answered your query,

Feel free to ask any further doubts.

Wishing your fiance a good health.

Thank you