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Suggest Treatment For Unconjugated Hyperbilirubinemia

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Posted on Wed, 16 Dec 2015
Question: My bilirubin is 1.21 and my bilirubin direct serum is 0.22.both are in high range. My digestive system is not
good. What is the reason and what should be done to recover.my bilirubin almost remains on this range only. ..I worried only about my liver and the local doctors here say that my body system is like that only but it sometimes come in proper range also.i am seriously concerned about this problem .kindly guide me.
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Answered by Dr. Amit Jain (52 minutes later)
Brief Answer:
It is unconjugated hyperbilirubinemia

Detailed Answer:
Hello! Thanks for putting your query in HCM. I am a Gastroenterologist (DM). Isolated increase in bilirubin has only few causes. Since direct bilirubin is less than 50% of the total bilirubin suggest that is unconjugated hyperbilirubinemia. Causes of isolated unconjugated hyperbilirubinemia are either haemolytic anemia or Gillbert's Syndrome.
To see for haemolytic anemia you need evaluation and some tests like complete haemogram with peripheral smear and absolute reticulocyte count. And if found abnormal the further evaluation for which you have to visit a Haematologist
And for Gillberts there is nothing to worry. It will never harm you in any way. Bilirubin will increase and resolve spontaneously and there is no medcine for it. What all you have to do is to avoid alcohol, and starvation
I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.
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Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Amit Jain

Gastroenterologist

Practicing since :2000

Answered : 1524 Questions

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Suggest Treatment For Unconjugated Hyperbilirubinemia

Brief Answer: It is unconjugated hyperbilirubinemia Detailed Answer: Hello! Thanks for putting your query in HCM. I am a Gastroenterologist (DM). Isolated increase in bilirubin has only few causes. Since direct bilirubin is less than 50% of the total bilirubin suggest that is unconjugated hyperbilirubinemia. Causes of isolated unconjugated hyperbilirubinemia are either haemolytic anemia or Gillbert's Syndrome. To see for haemolytic anemia you need evaluation and some tests like complete haemogram with peripheral smear and absolute reticulocyte count. And if found abnormal the further evaluation for which you have to visit a Haematologist And for Gillberts there is nothing to worry. It will never harm you in any way. Bilirubin will increase and resolve spontaneously and there is no medcine for it. What all you have to do is to avoid alcohol, and starvation I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.