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Suggest Treatment For Thalassemia With Abnormal RBC

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Posted on Mon, 2 Jun 2014
Question: Hi,
I am 28 years aged male, height 5'10'' and weight is 80 Kgs.
I dont have a disease history , apart from hair thinning.
I recently underwent CBC and Ferittin Test and below were my results:
TEST NAME          VALUE     UNITS     REFERENCE RANGE
                         
COMPLETE HEMOGRAM                         
TOTAL LEUCOCYTES COUNT     6.3     X 10³ / µL     4.4 - 11.0          
NEUTROPHILS          52.7     %     40-80          
LYMPHOCYTE PERCENTAGE     31.2     %     M:20-40; F:20-40
MONOCYTES          12.2     %     0-10          
EOSINOPHILS          3.7     %     0-6          
BASOPHILS          0.2     %     0-1          
TOTAL RBC           6.79     X 10^6/µL     Male : 4.3-5.9
                    Female : 3.5-5.0
HEMOGLOBIN          14.5     g/dL     Male : 13.3-17.7
                    Female : 11.7-15.7
HEMATOCRIT          47     %     Male : 39.8-52.2
                    Female : 34.9-46.9
MEAN CORPUSCULAR VOLUME      70     fL     76-100          
MEAN CORPUSCULAR HEMOGLOBIN      21     pg     27.0-33.0          
MEAN CORP.HEMO.CONC     31     %     33.4-37.0          
RED CELL DISTRIBUTION WIDTH (RDW CV)     16.4     fL     11.5-14.5          
PLATELET COUNT     183     X 10³ / µL     150-400          
PLATELET DISTRIBUTION WIDTH     15.4     %     10.00          
MEAN PLATELET VOLUME     9.5     fL     6.5-12.0          
ERYTHROCYTE SEDIMENTATION RATE     2     mm / hr     Male : 0-15
                    Female : 0-20
S. Ferittin 40ng/ml
Vid D3 45ng/ml
My Concern is my MCH, MCHC and MCV is slightly low and my S. Ferittin is 40ng/ml which is in the reference normal range (22-322 ng/ml).
Doc has suggested me iron supplements. My Mom is Anemic and has slightly low hemoglobin(around 9-10.5)
I was just concerned about Thalessemia trait as my RBC is slightly elevated and MCH, MCHC and MCV is slightly low. although in my whole family there is no history of Thalessemia ever.
I just want a second opinion on my CBC results and my concern

doctor
Answered by Dr. Dr. Rahul Kumar (7 hours later)
Brief Answer:
Iron deficiency anaemia

Detailed Answer:
Hello XXXXXXX
You just have iron deficiency anaemai.
Your reports typically suggest that.
Thalassemia presents with abnormal RBC.
If you are in doubt of thalassemia, please get a peripheral smear done.
Thalassemia can be diagnosed only with presence of abnormal red cells in peripheral smear.
Let me know if you have any other doubts.
Thank you
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. Rahul Kumar (2 hours later)
Is 40ng/ml Iron content is deficient enough to lower down MCHC, MCH, MVC?

Is RBC Count in my report abnormal enough to suggest thalassemia or should I continue with the Iron Suuplement and get a CBC done after sometime ?
doctor
Answered by Dr. Dr. Rahul Kumar (28 hours later)
Brief Answer:
Reports are normal

Detailed Answer:
Hello
40 ng/ml is not very low.
It is fine above 20.
You have a very mild anaemeia.
The reports dont suggest anything towards thalassemia.
Please dont worry.
Even then if you have doubts please get a peripheral smear of blood done.
It is the most important and easiest test to diagnose thalassemia.
Thank you
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Rahul Kumar

Dermatologist

Practicing since :2010

Answered : 6634 Questions

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Suggest Treatment For Thalassemia With Abnormal RBC

Brief Answer: Iron deficiency anaemia Detailed Answer: Hello XXXXXXX You just have iron deficiency anaemai. Your reports typically suggest that. Thalassemia presents with abnormal RBC. If you are in doubt of thalassemia, please get a peripheral smear done. Thalassemia can be diagnosed only with presence of abnormal red cells in peripheral smear. Let me know if you have any other doubts. Thank you