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Suggest Treatment For Osteoarthritis In Knee
Question: I have had malignant bone tumor in my knee years ago, with a second recurrence. At the time my orthopedic surgeons told me I could never take steroids or estrogen. Ten years later, I was given 1/2cc
of estrogen, which was after having a complete hysterectomy from malignancy at 26 years old. I received the estrogen only once, 4 months later I was on the table having a complete mastectomy of my right breast, removal of all lymph nodes on right side. Over the year's I began having osteoporosis in my knee. The deteriation progressed until I finally had to start living in a power chair, retiring early. The pain used to be only when I walked or put pressure on my knee. I get no relief from pain now. I can't sleep more than 2 hours without waking up in pain. I've taken various anti inflammatories with Carafate
for my stomach, as it tends to affect my stomach. I take hydrocodone for pain, which does not help.
I feel confident you being an orthopedic surgeon, you can answer my question about cortisone shots, or give me other advice which would help me. Thank you in advance for your help.
of estrogen, which was after having a complete hysterectomy from malignancy at 26 years old. I received the estrogen only once, 4 months later I was on the table having a complete mastectomy of my right breast, removal of all lymph nodes on right side. Over the year's I began having osteoporosis in my knee. The deteriation progressed until I finally had to start living in a power chair, retiring early. The pain used to be only when I walked or put pressure on my knee. I get no relief from pain now. I can't sleep more than 2 hours without waking up in pain. I've taken various anti inflammatories with Carafate
for my stomach, as it tends to affect my stomach. I take hydrocodone for pain, which does not help.
I feel confident you being an orthopedic surgeon, you can answer my question about cortisone shots, or give me other advice which would help me. Thank you in advance for your help.
Brief Answer:
explained
Detailed Answer:
Hello and Welcome
I appreciate your concern and want to let you know that I am here to help.
I want to emphasize the following points.
Many people can confuse osteoporosis and osteoarthritis.
Osteoporosis is a condition in which the bones become less dense and more likely to fracture.
Osteoarthritis (OA) is a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or small joints of the hands.
A single dose of Estrogen is not causative for breast malignancies.
Estrogen exposure should be avoided and is in fact contraindicated in your case.
The alternatives for you are the following once DEXA scan and 24 hour urine NTX or Hydroxyproline for assessing calcium loss and determining osteoporosis.
BISPHOSPHONATES LIKE ALENDRONATE
SERMS LIKE RALOXIFENE
CALCIUM AND VITAMIN D SUPPLEMENTS
If maximum pain relief and local cortisone shots don't relieve the symptoms then a surgical consult is advised esp with knee involvement i.e arthroscopy, osteotomy, and arthroplasty are the options that should be considered in consult with an orthopedic surgeon after a thorough physical exam.
In a recent development, the FDA has approved submicron diclofenac (Zorvolex) for the management of osteoarthritis pain. You may use a PPI with it avoid to protect your stomach.
wishing you best of health
thanks
explained
Detailed Answer:
Hello and Welcome
I appreciate your concern and want to let you know that I am here to help.
I want to emphasize the following points.
Many people can confuse osteoporosis and osteoarthritis.
Osteoporosis is a condition in which the bones become less dense and more likely to fracture.
Osteoarthritis (OA) is a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or small joints of the hands.
A single dose of Estrogen is not causative for breast malignancies.
Estrogen exposure should be avoided and is in fact contraindicated in your case.
The alternatives for you are the following once DEXA scan and 24 hour urine NTX or Hydroxyproline for assessing calcium loss and determining osteoporosis.
BISPHOSPHONATES LIKE ALENDRONATE
SERMS LIKE RALOXIFENE
CALCIUM AND VITAMIN D SUPPLEMENTS
If maximum pain relief and local cortisone shots don't relieve the symptoms then a surgical consult is advised esp with knee involvement i.e arthroscopy, osteotomy, and arthroplasty are the options that should be considered in consult with an orthopedic surgeon after a thorough physical exam.
In a recent development, the FDA has approved submicron diclofenac (Zorvolex) for the management of osteoarthritis pain. You may use a PPI with it avoid to protect your stomach.
wishing you best of health
thanks
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
You are right. I was diagnosed with osteoarthritis. My Dr. tested me for rheumatoid arthritis and the test was negative, not rheumatoid arthritis. The
reason I was in question, is because I have deformity in my knees and fingers.
So, you confirm it is safe for me to take cortisone injections. Also, do you know
the results from those people taking (Zorvolex)? Is it for pain or inflammation?
Thank you for your help.
reason I was in question, is because I have deformity in my knees and fingers.
So, you confirm it is safe for me to take cortisone injections. Also, do you know
the results from those people taking (Zorvolex)? Is it for pain or inflammation?
Thank you for your help.
Brief Answer:
Yes, its safe
Detailed Answer:
hi
Yes, they are safe. Cortisone injections into a joint can be beneficial in reducing joint pain while increasing function to a body part immobilized by inflammation.
Approval for the new indication of Zorvolex by FDA was based on a 12-week, randomized, placebo-controlled trial in 305 patients and data from a 12-month open-label safety study. The drug contains diclofenac as submicron particles approximately 20 times smaller than their original size, leading to faster dissolution and lower effective doses. Its for both pain and inflammation reduction.
Let me know if you have any query
Thanks.
Yes, its safe
Detailed Answer:
hi
Yes, they are safe. Cortisone injections into a joint can be beneficial in reducing joint pain while increasing function to a body part immobilized by inflammation.
Approval for the new indication of Zorvolex by FDA was based on a 12-week, randomized, placebo-controlled trial in 305 patients and data from a 12-month open-label safety study. The drug contains diclofenac as submicron particles approximately 20 times smaller than their original size, leading to faster dissolution and lower effective doses. Its for both pain and inflammation reduction.
Let me know if you have any query
Thanks.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Thank you for answering my questions and new information given me. Greatly appreciated. I will be contacting an orthopedic surgeon soon. XXXXXXX XXXXXXX
Brief Answer:
You are welcome.
Detailed Answer:
hi XXXXXXX
Hope you are feeling better,
I am glad I was of some assistance. You may let me know of your progress and follow up with your doctor. I will be glad to assist you along the way. Let me know if you have any other clarification that you need.
thanks.
You are welcome.
Detailed Answer:
hi XXXXXXX
Hope you are feeling better,
I am glad I was of some assistance. You may let me know of your progress and follow up with your doctor. I will be glad to assist you along the way. Let me know if you have any other clarification that you need.
thanks.
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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