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Suggest Treatment For Calcified Focus In The Brain

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Posted on Tue, 8 Jul 2014
Question: My daughter had a fit in 2005 and CT scan was suggestive of calcified granuloma in right frontal lobe in 2005. She was put on zeptol for up to 5-6 years. Later in 2008 she experienced another fit . EEG showed abnormal awake EEG record showing generalized epileptic discharges. background 8-9 hz, 20-30 uv posterior dominant reactive to eye opening alpha activity symmetricaly. alpha dropout during sleep, electrode artefacts seen, occasional 1-2 hz spikes, and slow wave discharges seen over both posterior head region, occasional generalized sharp waves seen, no activation with hyperventilation and photic stimulation Kindly advise precautions and further course of treatment. Is this curable?
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Answered by Dr. Saumya Mittal (27 hours later)
Brief Answer:
Some information provided

Detailed Answer:
Hi there, I am Dr Saumya Mittal, MD.And I am going to try to answer your query.

The fact remains that your daughter has a calcified focus in the brain. Now the calcified lesion is a focus from where the brain keeps getting abnormal electrical signals. These result in seizures. Unfortunately, calcified lesions, anywhere in the body, do not dissolve.
So once formed, probably after an infection, the calcified focus is almost permanently (unless removed surgically- which may have its own complications, and a risk of seizure).

In view of the almost permanent nature of the lesion, the medicines need to continue regularly. The skipping of doses may actually trigger a seizure, as may other risk factors like incomplete sleep, or intake of other medicines that may increase excretion of the medicines.

Also, please make sure she is away from potentially dangerous activities like driving or swimming. The reasons can be obvious if you consider the dangers that may happen if a seizure happens while performing such an activity.
In fact in some countries, a doctor is duty bound to report to authorities the condition of a person whereupon a license is revoked.

I must add, given a regular medicine, and taking the precautions, the person can lead a normal lie, save for the inconvenience caused by limiting certain activities like driving.

And no, in her condition, I don't think its genetically transmissible.

Best of luck
In case you want to ask a more specific query, please feel free to ask a follow on query.
Dr Mittal
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Saumya Mittal

Diabetologist

Practicing since :2004

Answered : 2897 Questions

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Suggest Treatment For Calcified Focus In The Brain

Brief Answer: Some information provided Detailed Answer: Hi there, I am Dr Saumya Mittal, MD.And I am going to try to answer your query. The fact remains that your daughter has a calcified focus in the brain. Now the calcified lesion is a focus from where the brain keeps getting abnormal electrical signals. These result in seizures. Unfortunately, calcified lesions, anywhere in the body, do not dissolve. So once formed, probably after an infection, the calcified focus is almost permanently (unless removed surgically- which may have its own complications, and a risk of seizure). In view of the almost permanent nature of the lesion, the medicines need to continue regularly. The skipping of doses may actually trigger a seizure, as may other risk factors like incomplete sleep, or intake of other medicines that may increase excretion of the medicines. Also, please make sure she is away from potentially dangerous activities like driving or swimming. The reasons can be obvious if you consider the dangers that may happen if a seizure happens while performing such an activity. In fact in some countries, a doctor is duty bound to report to authorities the condition of a person whereupon a license is revoked. I must add, given a regular medicine, and taking the precautions, the person can lead a normal lie, save for the inconvenience caused by limiting certain activities like driving. And no, in her condition, I don't think its genetically transmissible. Best of luck In case you want to ask a more specific query, please feel free to ask a follow on query. Dr Mittal