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Suggest Treatment For Alcoholic Liver Disease

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Posted on Wed, 8 Apr 2015
Question: Just had blood work that revealed AST 273, ALT 69, and everything else WNL. In 11/13 AST was 39, ALT 14. In 11/13 I dramatically reduced alcohol intake to once a month. Before that, was 1-2 drinks 4-5 times a week. Drank moderate to heavy in 20s and early 30s. In 3/12 AST 33, ALT 11. Last alcohol intake was 5 weeks prior to lab work. I think it's pretty safe to say this is alcohol induced liver disease (AST:ALT ratio >2). My questions are about prognosis at this point. If I stop alcohol permanently now, should this disease process stabilize? What are my chances at not progressing to cirrhosis and liver failure (if I don't have cirrhosis already)? What tests should I expect to get (US, lab work, biopsy, etc.)?I am 40yo, white female, 5'7", 140 lb. I started taking bupropion XL 150 mg QD about 2 weeks prior to lab work. Also began vigorous exercise (weight training) 1 week prior to lab work and had severe muscle soreness. Been drinking about 4 energy drinks (Rockstar) a week for past 5 years. Also take Pristiq 100mg QD x 3 years, VitD3 2000 IU QD, multivitamin QD.
doctor
Answered by Dr. Dr.P.Ratnakar Kini (1 hour later)
Brief Answer:
Answer given below

Detailed Answer:
Hi,
Thanks for posting your query.
I am Dr.R.K and I am pleased to assist you.

Yes, as you said you are having features of alcoholic liver disease.
A PT/INR test should be done to know how the disease would progress and to plan the treatment.

If you stop alcohol permanently, and there is no cirrhosis, you may recover completely in 3-6 months time.
You can get a fibroscan done to see if cirrhosis has already set in.

You can take s.adenosylmethionine supplements for good recovery.

I hope that answers your query.
Let me know if you have any more questions.
Regards,
Dr.R.K.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr.P.Ratnakar Kini (8 hours later)
Given my past lab results, and not being symptomatic, is it reasonable to believe i am in the early stages or is cirrhosis still a real possibility? How often is someone with my presentation already in the cirrhosis stage? Thank you for your time.
doctor
Answered by Dr. Dr.P.Ratnakar Kini (4 hours later)
Brief Answer:
Early cirrhosis usually asymptomatic

Detailed Answer:
Hi,
Early cirrhosis is usually asymptomatic.
Your lab results show you are having alcoholic hepatitis.
Early cirrhosis cannot be ruled out as it is usually asymptomatic.
You can see the albumin globulin ratio. If it is less than one , it indicates chronic liver disease, cirrhosis in this case is already set in.
The other ways to know are an ultrasound/Fibroscan.

Let me know if I can assist you further.
Regards,
Dr.R.K.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr.P.Ratnakar Kini

Gastroenterologist

Practicing since :1994

Answered : 2215 Questions

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Suggest Treatment For Alcoholic Liver Disease

Brief Answer: Answer given below Detailed Answer: Hi, Thanks for posting your query. I am Dr.R.K and I am pleased to assist you. Yes, as you said you are having features of alcoholic liver disease. A PT/INR test should be done to know how the disease would progress and to plan the treatment. If you stop alcohol permanently, and there is no cirrhosis, you may recover completely in 3-6 months time. You can get a fibroscan done to see if cirrhosis has already set in. You can take s.adenosylmethionine supplements for good recovery. I hope that answers your query. Let me know if you have any more questions. Regards, Dr.R.K.