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Suggest Remedy To Deal With Anger Management Issues

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Posted on Mon, 10 Nov 2014
Question: Yes, my husband is taking IC Divalproex 500 mg SOD ER one time a day at bedtime. He is also taking IC Quetiapine Fumurate 100 mg two times a day one mid morning and one at bedtime (seroquel). He is very sleepy during the day now and his mother is worried about possible drug interactions. I did talk to his Psychiatrists office (Dr. XXXXXXX Packo, Summa Western Reserve Health System, Hudson, Ohio. She has instructed my husband to cut back on the seroquel to one dose at bedtime along with the depakote at bedtime. My mother-in-law thinks it is unsafe to even take those medications together at all. Is she right. My husband does have anger management issues along with a learning disability (dyslexia). He has gotten out of control with his anger many times and I just want to get the best mix of medications without him being overly tired. He can be unpredictable and sometimes his family doesn't fully his mental health issues (there is partial denial there). Do you concur with Dr. XXXXXXX Packo.
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Answered by Dr. Shoaib Khan (1 hour later)
Brief Answer:
I do concur with Dr. XXXXXXX Packo

Detailed Answer:
Hello ma'am and welcome.

Thank you for writing to us.

I have gone through your query with diligence and would like you to know that I am here to help. One of the most important objectives to achieve successful treatment for a patient with psychiatric or psychological issues is family support. In most cases, this is not present simply because the family members have either never seen, heard or experienced symptoms relating to such conditions and so think that it is all in the head. So I do understand the situation, but I wish you would try to speak to his family and help them understand him better.

As for a suspected drug interaction between divalproex SOD ER and seroquel, I do not think an interaction can result in drowsiness that you seem to be noticing. But in my opinion, the drowsiness could simply be a side effect of the medications themselves. So I do concur with Dr. XXXXXXX that these medications will in fact help him, but the dosage could be causing drowsiness. If at all the drowsiness continues then we might have to consider making changes to his treatment regimen. So let us first wait and observe how he responds to the latest changes advised by Dr. XXXXXXX

The possible interactions seen from using these two medications in men are few and rare, and include changes in blood glucose levels, obesity, mild aggression, inflammation of the pancreas, and increase in blood cholesterol levels.

I hope you find my response both helpful and informative ma'am. I hope your husband feels much more active after a reduction in dosage and with the current changes made by Dr. XXXXXXX but if at all he does not then please report to her and request for a change in the regimen.

Best wishes.
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

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Suggest Remedy To Deal With Anger Management Issues

Brief Answer: I do concur with Dr. XXXXXXX Packo Detailed Answer: Hello ma'am and welcome. Thank you for writing to us. I have gone through your query with diligence and would like you to know that I am here to help. One of the most important objectives to achieve successful treatment for a patient with psychiatric or psychological issues is family support. In most cases, this is not present simply because the family members have either never seen, heard or experienced symptoms relating to such conditions and so think that it is all in the head. So I do understand the situation, but I wish you would try to speak to his family and help them understand him better. As for a suspected drug interaction between divalproex SOD ER and seroquel, I do not think an interaction can result in drowsiness that you seem to be noticing. But in my opinion, the drowsiness could simply be a side effect of the medications themselves. So I do concur with Dr. XXXXXXX that these medications will in fact help him, but the dosage could be causing drowsiness. If at all the drowsiness continues then we might have to consider making changes to his treatment regimen. So let us first wait and observe how he responds to the latest changes advised by Dr. XXXXXXX The possible interactions seen from using these two medications in men are few and rare, and include changes in blood glucose levels, obesity, mild aggression, inflammation of the pancreas, and increase in blood cholesterol levels. I hope you find my response both helpful and informative ma'am. I hope your husband feels much more active after a reduction in dosage and with the current changes made by Dr. XXXXXXX but if at all he does not then please report to her and request for a change in the regimen. Best wishes.