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Suggest Medicines For Resistant H. Pylori Infection
Question: What meds do you recommend for resistant H. pylori infection. I was treated with Amoxicillin and Clarithromycin for two weeks, but I still have H. pylori. I do not smoke or eat any acid producing foods. My doctor has given me two more weeks worth of Amoxicillin and Clarithromycin.
Brief Answer:
Alternative triple or quadruple therapy is used
Detailed Answer:
Hi,
Since you are taking amoxycillin + clarithromycin with antacid (ranitidine or omeprazole/ pantoprazole) and if this triple combination fails then, you can try one of the regimens from given below according to your resistant strains.
This alternative regimens I am giving below is not to confuse you but the aim is to clear all the possible regimens what you can try only after your physician's consultation.
1) alternative triple drug therapy
(i) omeprazole 40 mg daily+ amoxycillin 500 mg thrice a day + metronidazole400 mg thrice a day for 7 days full course.
(ii) ranitidine 300 mg daily+ amoxycillin 750 mg thrice a day + metronidazole 500 mg thrice a day for 12 days course.
(iii) colloidal bismuth subcitrate 120 mg 4 times daily + tetracycline 500 mg 4 times daily + metronidazole 400 mg 4 times daily for 2 weeks.
(2) quadruple therapy
pantoprazole/ rabeprazole 40 mg twice daily+ colloidal bismuth subcitrate 120 mg 4 times daily+ tetracycline 500 mg 4 times daily+ metronidazole 500 mg 4 times daily for 7 days full course.
Alternative triple or quadruple therapy is used
Detailed Answer:
Hi,
Since you are taking amoxycillin + clarithromycin with antacid (ranitidine or omeprazole/ pantoprazole) and if this triple combination fails then, you can try one of the regimens from given below according to your resistant strains.
This alternative regimens I am giving below is not to confuse you but the aim is to clear all the possible regimens what you can try only after your physician's consultation.
1) alternative triple drug therapy
(i) omeprazole 40 mg daily+ amoxycillin 500 mg thrice a day + metronidazole400 mg thrice a day for 7 days full course.
(ii) ranitidine 300 mg daily+ amoxycillin 750 mg thrice a day + metronidazole 500 mg thrice a day for 12 days course.
(iii) colloidal bismuth subcitrate 120 mg 4 times daily + tetracycline 500 mg 4 times daily + metronidazole 400 mg 4 times daily for 2 weeks.
(2) quadruple therapy
pantoprazole/ rabeprazole 40 mg twice daily+ colloidal bismuth subcitrate 120 mg 4 times daily+ tetracycline 500 mg 4 times daily+ metronidazole 500 mg 4 times daily for 7 days full course.
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Above answer was peer-reviewed by :
Dr. Ashwin Bhandari
Answered by
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