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Suggest Medication When Diagnosed With Diabetes And Kidney Issues

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Posted on Thu, 27 Aug 2015
Question: I have diabetes type two and with kidney problems which medicine you recommend?
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Answered by Dr. Shehzad Topiwala (23 minutes later)
Brief Answer:
Diabetes

Detailed Answer:
I follow your question.

There are some diabetes medications that should be avoided when the kidney function is below a certain threshold.

However, it is not the objective of this forum to give precise medication recommendations. But I will give you broad guidance on how I approach my patients with diabetes and kidney problems, regarding medicines.

1 Metformin should not be used when there is a significant decline in kidney function.

2 A class of medications called Alpha glucosidase inhibitors should be avoided in this situation too.

3 Some medications' doses need to be reduced when the kidney function falls.
This includes some DPP 4 inhibitors, wight he exception of the one you are on i.e. Tradjenta
You have mentioned 50 mg but that is likely a typo as the correct dose is 5 mg

4 A new class of medications called SGLT2 inhibitors are also not to be used in kidney problems

5 A family of medications called Sulfonylureas must be avoided or used with caution when kidney function starts declining.

6 Medicines in the category of 'Thiazolidenediones' are okay to take though

7 Insulin is safe regardless of kidney function. However, lower doses than usual need to be carefully utilised.
Note: For further follow-up, discuss your blood glucose reports with our diabetologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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Suggest Medication When Diagnosed With Diabetes And Kidney Issues

Brief Answer: Diabetes Detailed Answer: I follow your question. There are some diabetes medications that should be avoided when the kidney function is below a certain threshold. However, it is not the objective of this forum to give precise medication recommendations. But I will give you broad guidance on how I approach my patients with diabetes and kidney problems, regarding medicines. 1 Metformin should not be used when there is a significant decline in kidney function. 2 A class of medications called Alpha glucosidase inhibitors should be avoided in this situation too. 3 Some medications' doses need to be reduced when the kidney function falls. This includes some DPP 4 inhibitors, wight he exception of the one you are on i.e. Tradjenta You have mentioned 50 mg but that is likely a typo as the correct dose is 5 mg 4 A new class of medications called SGLT2 inhibitors are also not to be used in kidney problems 5 A family of medications called Sulfonylureas must be avoided or used with caution when kidney function starts declining. 6 Medicines in the category of 'Thiazolidenediones' are okay to take though 7 Insulin is safe regardless of kidney function. However, lower doses than usual need to be carefully utilised.