Brief Answer: You need to use preservative free eye drops. Detailed Answer: Hello Welcome to Health care magic Iam Dr. Dadapeer K, an Ophthalmologist and I answer health problems related to eye. Eye irritation is a common problem seen in patients using antiglaucoma drugs. Most of the eye irritation is because of presence of preservatives like Benzalkonium chloride which are used along with the glaucoma medications as preservative. Hence if you are having significant eye irritation because of use of antiglaucoma drugs you need to consider use of preservative free antiglaucoma drugs. Most of the antiglaucoma eye drops like prostaglandins, timolol, dorzolamide are available in preservative free from and you need to shift to these eye drops depending on the eye drops you are using. Hence please consult your eye doctor for prescription of preservative free eye drops to prevent eye irritation. Melatonin is used for the treatment of insomnia and Circadin is a prolonged release tablet containing melatonin with long duration of action. Hence this can be used for treatment of insomnia. Hope I have answered your questions. Thank you

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