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Suffering from fever. Done with several tests and diagnosed with typhoid. Still having fever. Underlying causes?

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Practicing since : 2007
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my sister is suffering from fever since last 3-4 months her fever remains between 99.00 f to 99.80 f, we have consulted many doctors but no relief several test have been done like tlc,dlc urineculture, ppd, ultrasound, xray every thing is normal only typhoid is diagnosed and from last 3 months every doctor is treating for the same but still the fever persists what shall we do? what could be cause of her fever?
Posted Mon, 9 Sep 2013 in Infections
 
 
Answered by Dr. Srikanth Reddy 43 minutes later
Brief Answer:
Need to rule out tuberculosis.

Detailed Answer:
Hello,
Thanks for choosing health care magic for posting your query.
I have gone through your question in detail.
There could be many reasons for such fevers and such fever is called pyrexia of unknown origin (PUO). Of all the tests that you have mentioned,you have not mentioned tests for tuberculosis. Tuberculosis could be responsible for this kind of fever.
Secondly you should get her tested for HIV as well. HIV can spread in many ways and its always best to get examined if there is this long a fever. Nothing wrong in being cautious.
Malaria can also lead to such long standing fevers and serological tests of malaria can be useful for this purpose.
Hope I am able to answer your concerns.
If you have any further query, I would be glad to help you.
If not, you may close the discussion and if possible you may rate the answer for me, so that I get a good feedback.
In future if you wish to contact me directly, you can use the below mentioned link:
bit.ly/dr-srikanth-reddy

Wish you good health,
Dr. Srikanth Reddy M.D.
Above answer was peer-reviewed by
 
Follow-up: Suffering from fever. Done with several tests and diagnosed with typhoid. Still having fever. Underlying causes? 39 hours later
I have mentioned about tb test that is ppd test or tuberculin test and it negative.
so what could be the possible reason.
 
 
Answered by Dr. Srikanth Reddy 1 hour later
Brief Answer:
Other tests for tuberculosis

Detailed Answer:
Hello,
I understand that you have mentioned PPD test for tuberculosis but there are other Ag and Ab tests for tuberculosis which need to be done to confirm it once again as the fever has persisted for long.
My other suspicion of Malaria and HIV still persist. You should get those investigated.
Other possibility is benign eosinophilia or filariasis which can present with such kinds of fever.
If the fever still persists then a MRI scan of brain can be done. Many times subclinical infections of layers of brain can lead to such fevers.
Hope I am able to answer your concerns.
If you have any further query, I would be glad to help you.
If not, you may close the discussion and if possible you may rate the answer for me, so that I get a proper feedback.
In future if you wish to contact me directly, you can use the below mentioned link:
bit.ly/dr-srikanth-reddy

Above answer was peer-reviewed by
 
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