Question: hello Doctor , I m indian and leave in Delhi. I had a low risk exposure (protected sex with a CSW) on 18th Feb. after 24 days i felt worry of HIV (no symptom). I went to a Doctor (MD in Medicine and sexology). Doctor took blood sample and went for complete and expansive STD package ( HSV1/2, CD4, CD8, CD3, T cell and HIV1/2 test by fully automatic 4th generation western blot architecture. All came out negative and Ok. Still i was worried and asked doctor for HIV 1/2 and P24 combo (CMIA) at 44 days. instead of that he went for PCR RNA HIV and repeated the same western blot HIV test. Western blot test came all negative again at 44 days but PCR RNA TEST GAVE 225 COPIES/ML. looking at high possibility of false positive result in PCR test. it was not conclusive as CDC guidelines says a positive PCR RNA TEST SHOULD BE CONFIRMED BY antibody test only. For safety Dr. starts anti drugs propelix TEEVIR (Tenofovir Disofroxil fumarale/ Emtricitabine and Elavirenz 300 mg/ 200mg / 600 mg) one tab a day. I was too confused and today at 47 days post exposure I went for a HIV 1/2 & P24 Combo test in Dr. Lal Path Lab a renowned Lab in INdia, which gives index value of 0.1 and non reactive. now i am most confused as 47 days result of combo test should be highly accurate. and PCR test result may be false possitive. NOw My tests ar as follows: -4th generation western blot architecure at 24 days - all negative -4th generation western blot architecure at 44 days - all negative - PCR RNA at 44 days - Positive with 225 copies/ml. - HIV 1/2 & P24 Combo (CMIA) at 47 Days - non reactive index-0.1 my question are as follows: 1)Now should I continue with the anti drugs mentioned above or weight for result of 90 days HIV antibody test. My Dr. sugestted to take the tab for safety purpose looking at the PCR result. I have started the medicine from yesterday. 2) if i continue taking medicine and 90 days HIV 1/2 & P24 Combo (CMIA) negative results can be conclusive. is there any case that I am taking anti drugs and for that the 90 days result may come negative even though possibilty of positive result without medicine. Sorry for the long description. please help. I am becoming helpless, worry and sleepless and i have already spent a lot for this confusion.

Hl doctor sir Yes I am continuing with the medicine. I also want to know that is the medicine has no side effect, if any possibility of negative result. What is the possibility of false positive PCR result. Looking at the negative result of combo test at 47 days is highly accuratre Is it normal after 44days PCR test gives so less load in the case of infection. What is the chance of my getting negative. I have gone through the.body.com such cases happened I.e positive PCR test followed by series of negative antibody antigen test including at 90 days.

Hi. thanx. you have not told that Is it normal after 44 days post exposure PCR RNA test gives so less load in the case of infection. please advise me doctor because i guess this drug may harm other organs too as per adverse effect explain by you. Doctor told me to take this for one month only.

Hi Doctor, I am again writing because I am worry taht I may not know my actual HIV Status ever. After taking ART for one month the viral load may become undetectable and that time 90 days will be completed and my 90 days antibody test will definitely be negative. I was so worry and I am not able to believe that I am HIV positive. so I Have again taken a PCR RNA quantification test from another Lab i.e Dr. Lal Path Lab, New Delhi and it came out target not detected means HIV-1 Virus RNA not found in blood sample. the test name is HIV-1 RNA quantitative real time PCR test @ ( real time PCR using Cobas Ampliprep & Taqman.). the lower limit of detection is 20 copies/ml. I am now more confused.I have shown the report to my doctor. he is telling that it may be due to taking 3 days of ART or he do not have much faith on Lab set up of Dr. Lal path lab for this type of test.He is still insisting to continue with ART. this time he changes ART to Recovir EM as i was not feeling well with earlier ART. He told after one month of ART he will take the PCR test again in the same Lab at XXXXXXX Mumbai and then he can conclude. This Dr. is not my regular Doctor and I met him only to diagnosis the HIV status. I never knew him before. Now I have started to feel that I may be fallen under false positive for ever and i will never actually know my actual status. Now my test summary is as follows: - 44 th days PCR from a Lab Called Infexn at XXXXXXX mumbai sample received at Lab one day after collection from New Delhi. result 225 copies/ml. - 46th day -ART taken after receiving the report. - 47th day -ART taken - 48th day -ART taken - 49 th day - ART not taken as i was not feeling well. -50 th day PCR RNA in Dr, Lal , New delhi- result target not detected. Now I need Help from you my questions are as follows: 1) Is this negative PCR result from Dr. Lal Path Lab, New Delhi is due to taking only 3 days of ART. 2) Can PCR RNA test from Dr. Lal Path lab be false negative. 3) should I still continue with the ART (Recovir EM) 4) or should I wait for 90 days antibody test for conclusion. other wise with ART the antibody test may not be properly conclusive and documented. 5) If the ART taken by a HIV negative person, will there be any effect in CD4, CD8 or CD3 count or any other health problem. Thanks and expect pointwise clear sugestions.

Hi Thanx doctor Only three days ART can reduce all 225 copies RNA. After three days ART I stopped for one day and then PCR RNA TEST TAKEN from Lal Path Lab Thanx

HI During taking ART MY LIP Was drying and swelling. While asking Doctor he was telling that your immune system is fighting the virus. That is why you are getting reaction from ART. Is it true. Is Drying and swelling the lip and slight normal sore on lip is symptom of Hiv. I do not have other symptom Thanks

Hi Doctor, There is no significant sore on lip, gum or inside mouth. I have misguided you sir. those are little crack on the dry lip. I often suffer with this even in summer season also. It was seen during taking the ART with slight swell. I will upload the picture later.