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Prozac 40 Mg,50 Mg Tramadol.Ok Together?

Posted on Tue, 22 May 2012

Question: I have been taking 40 mg prozac for almost a month now. Before that, i was on 20 mg for 6 weeks and my doctor increased the dosage. I am wondering if it will be ok for me to take 50 mg of tramadol with the prozac?

Answered by Dr. Rhea Chanda (11 minutes later)

Hello,

Thanks for your query.

Tramadol is known to have serious drug interactions with prozac. They have reported to produce seizures when taken together.

So do not take them in combination.

Hope I have answered your query. I am available for follow ups.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rhea Chanda (1 hour later)

What are the chances of an interaction happening? Isn't it very rare?

Answered by Dr. Rhea Chanda (6 minutes later)

Hi and thanks again.

The drug interaction that occur invivo vary among individuals. It is difficult to predict the chances of such interactions. Its not a rare occurrence. It is considered as a clinically significant interaction.

Since the interaction can produce a serious complications, I do not recommend you to take them together.

Regards,

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar