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Overdosed On Warfarin, Had Seizures After Knee Surgery. Can Warfarin Cause Seizure?

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Posted on Sat, 9 Jun 2012
Question: i was taking warfarin and ended up over dosing and ended in hospital receiving platlets and started having seizures later on after having another knee surgery. and i was wondering if this drug can cause seizure
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Answered by Dr. Robert Galamaga (35 minutes later)
Hello and thanks for the query.

Warfarin is not known to cause seizures. As you know - too much warfarin can cause a high risk for bleeding as you experienced. Several things may cause the warfarin level to be elevated including a low dietary intake of vitamin K or any infection of the bowels which affects the normal vitamin K producing bacteria which are native to the bowels.

I would suspect some other cause of the seizure such as pain medication, anesthesia or some other medication which lowered the threshold of your body to allow a seizure to occur. Maybe a good and careful review of your entire hospital course by your doctor would help get to the bottom of it.

I thank you again for the query and hope my response served to be helpful. If you have any additional concerns I would be happy to address them.

Sincerely,

Dr. Galamaga
Above answer was peer-reviewed by : Dr. Raju A.T
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Dr. Robert Galamaga

Oncologist

Practicing since :2002

Answered : 2635 Questions

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Overdosed On Warfarin, Had Seizures After Knee Surgery. Can Warfarin Cause Seizure?

Hello and thanks for the query.

Warfarin is not known to cause seizures. As you know - too much warfarin can cause a high risk for bleeding as you experienced. Several things may cause the warfarin level to be elevated including a low dietary intake of vitamin K or any infection of the bowels which affects the normal vitamin K producing bacteria which are native to the bowels.

I would suspect some other cause of the seizure such as pain medication, anesthesia or some other medication which lowered the threshold of your body to allow a seizure to occur. Maybe a good and careful review of your entire hospital course by your doctor would help get to the bottom of it.

I thank you again for the query and hope my response served to be helpful. If you have any additional concerns I would be happy to address them.

Sincerely,

Dr. Galamaga