Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
178 Doctors are Online

Oesophageal manometry test showed weak peristalsis with large peristaltic defects. Sugggestions

User rating for this question
Very Good
Answered by

Practicing since : 2000
Answered : 1410 Questions
For 4 years I have had a stomach disorder where I experience pain (up to 8/10) in my stomach, bloating and less often a sense of fullness. All PPI / H2 antagonist and Baclofen medication has had nil response. I have had the following tests carried out and all have been negative/normal: CT scan, ultrasound, 3 x endoscopy including biopsy, blood tests for diseases such as Crohns disease and Lupus disease, C25, helicobacter pylori, barium swallow and meal, nuclear imaging (gastric emptying), Bravo pH monitoring. I have been treated for Helicobacter pylori with nil response. My symptoms are erratic and chaotic and usually occur late afternoon and evening but never overnight. The only relief I can get is lying down. The pain can be caused by drinking coffee, alcohol and eating spicy foods but these beverages/food may not cause the pain at other times. Since the problem began I have been on a strict diet to eliminate these foods as well as soft drinks, rich foods, onions, garlic, leeks, but the problem continues. I have been on two elimination diets. The low FODMAP diet and an elimination diet for amines, salicylates and glutamates with no improvement of symptoms. I had the oesophageal manometry test and this showed: Weak peristalsis with large peristaltic defects; normotensive UOS; normotensive LOS. I also had the oesophageal multi channel intraluminal impedance 24 hour test and this test showed: physiological distal oesophageal acid reflux; Increased weak acid oesophageal reflux; normal total oesophageal bolus exposure; normal proximal oesophageal reflux; no symptoms association with reflux events. I am female and 50 years of age; have very good health otherwise; I exercise 5 x week (running and gym); I have little stress in my life; I don’t have children; I do not have food allergies nor food intolerances. My husband and I grow our own vegetables and fruit and these foods form a large part of my diet. I am 5’ 3 “ and weigh 50kgs. My cholesterol levels are 3.2. I take no medications for any other conditions. I would be grateful if you could any advice on my problem.
Posted Tue, 31 Dec 2013 in Digestion and Bowels
Answered by Dr. Amit Jain 3 hours later
Brief Answer: Please see the details Detailed Answer: Hello! Thanks for putting your query in XXXXXXX I am a Gastroenterologist (DM). Your symptoms suggest that you are suffering from dyspepsia with reflux symptoms. So PPI alone will not work well, take a prokinetic agent like itopride along with a PPI like ilaprazole. Continue with less fatty diet, avoid tea or coffee and spicy food. Don't lie soon after meals at least for 2 hours. Also continue with exercise. You are already following healthy life style. I hope I have answered your query and this will help you. If you have any further query I will be happy to answer that too. Remain in touch and get-well soon.
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to

The user accepted the expert's answer

Ask a Gastroenterologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor