Brief Answer: As a part of evaluation for abnormal bone marrow. Detailed Answer: Hi, thanks for writing to XXXXXXX I feel that your treating doctor might have suspected some Hematological disorder as the cause of abnormal bone marrow presentation in your MRI scans. There are number of causes that produce signal alteration on MRI scans and show up as abnormal bone marrow density. The causes include include - Variants of normal - marrow reconversion - tumor (myeloproliferative disorders, metastatic or primary) - radiation - an occult fracture - degenerative change - infection - inflammatory arthritis - osteonecrosis. Generally, Acute leukemias or solitary plasmacytoma's present as abnormal bone marrow densities in the vertebral column. And their presence can be suggested by having a blood lab work which shows abnormal blood cells under microscopy. A bone marrow aspiration & biopsy are needed to establish the correct diagnosis. Hope I have answered your query. Happy to help further Regards

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