Brief Answer: no interactions known Detailed Answer: HI, thanks for using healthcare magic Melatonin is used to help with some types of sleep disorders. It helps in the sleep cycle. In terms of interactions, melatonin is not similar in structure or metabolism to aspirin or statin drugs. This means that there is no interaction. The allergy to aspirin and to the statins would not mean that there is a risk of allergy to melatonin. In terms of glaucoma, there are different types of medications that can be used for glaucoma. There is a possibility of a minor interaction with only one of these glaucoma agents, timolol, this interaction is actually a positive one. The use of melatonin and timolol together can possibly decrease any toxicity related to timolol. It can decrease sleep disturbance related to the timolol. If you are using other glaucoma meds, there is no known interaction with melatonin. You can consider the use of the melatonin. I hope this helps , feel free to ask any other questions

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