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Is Long Term Peptic Ulcer Disease Related To Gastric Carcinoma?

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Posted on Fri, 31 Oct 2014
Question: How likely is long term peptic ulcer disease related to gastric carcinoma and the death of a person dying from both? My father was a WWII POW and developed bleeding ulcers and was diagnosed having PUD until his death in 1997. He also had H-Pylori that was never treated. His records show he also had pleurisy and hepatitis B if this helps. PLEASE help. I am in dire need of a positive answer from a professional doctor that links peptic ulcer disease to gastric hemorrhage and gastric carcinoma. Thank you so much for your time.
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Answered by Dr. Karen Steinberg (59 minutes later)
Brief Answer:
H. pylori has been linked to gastric cancer

Detailed Answer:
Hi,
H. pylori has been linked with both peptic ulcer disease and gastric cancer, so it is very possible this was all related and led to your father's death. Certainly either cancer or ulcers could cause gastric hemorrhage.

If he had chronic hepatitis B, it is also possible that he had developed cirrhosis. This could cause varicose veins in the stomach and result in gastric hemorrhage as well. Chronic hepatitis can also cause liver cancer. Treatment for chronic hepatitis B has only recently become available.

I would suggest that it is very likely that the untreated H. pylori, chronic peptic ulcer disease, and gastric cancer were all related. H. pylori has been classified as a carcinogen since 1994, and is a primary risk factor for peptic ulcers and cancer of the stomach.

Hope this answers your query. If you have further questions, I would be happy to answer them.
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Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
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Answered by
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Dr. Karen Steinberg

Internal Medicine Specialist

Practicing since :1981

Answered : 824 Questions

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Is Long Term Peptic Ulcer Disease Related To Gastric Carcinoma?

Brief Answer: H. pylori has been linked to gastric cancer Detailed Answer: Hi, H. pylori has been linked with both peptic ulcer disease and gastric cancer, so it is very possible this was all related and led to your father's death. Certainly either cancer or ulcers could cause gastric hemorrhage. If he had chronic hepatitis B, it is also possible that he had developed cirrhosis. This could cause varicose veins in the stomach and result in gastric hemorrhage as well. Chronic hepatitis can also cause liver cancer. Treatment for chronic hepatitis B has only recently become available. I would suggest that it is very likely that the untreated H. pylori, chronic peptic ulcer disease, and gastric cancer were all related. H. pylori has been classified as a carcinogen since 1994, and is a primary risk factor for peptic ulcers and cancer of the stomach. Hope this answers your query. If you have further questions, I would be happy to answer them.