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Is It Safe To Take Duromine Along With Levothyroxine?

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Posted on Tue, 13 Jan 2015
Question: Hi. I have had a total Thyroidectomy almost 3 weeks ago. Since surgery I am on 100mcg of Levothyroxine ongoing. My family doctor has prescribed 30mg Duromine and knew I was having surgery. Said should be fine to take once hormone levels are stabilised. Pharmacist was concerned about the combination and the Dr Professor surgon is on leave. Have read online that Duromine should not be taken with thyroid medication.

Any thoughts please?
30year old female
doctor
Answered by Dr. Shehzad Topiwala (1 hour later)
Brief Answer:
Thyroid/duromine

Detailed Answer:
There is no known direct interaction between duromine and levothyroxine, that is of clinical significance. This is to the best of my knowledge of published scientific literature.

In general, levothyroxine should be taken with water on an empty stomach 30 to 60 minutes before breakfast. So it is advisable to take duromine and for that matter any other medications/tablets after this time gap.

I see it has been 3 weeks since your thyroid surgery. When I see someone like you in my practice I typically run blood tests for thyroid function (TSH and Free T4) about 4 to 6 weeks after surgery to ensure appropriateness of the levothyroxine dose. It may require fine tuning for the first couple months to arrive at the dose appropriate for you.

There is no direct conflict between the two medications. However, it would be reasonable to wait till levothyroxine dose is stable in the desired range, before duromine is introduced. The reason for this is that some of the effects and side effects of duromine (such as weight loss, rapid heart rate, high blood pressure, sleeplessness) can mimic those of excess levothyroxine doing. So if both are being taken together it can become difficult to distinguish between the impact of the two medications.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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Is It Safe To Take Duromine Along With Levothyroxine?

Brief Answer: Thyroid/duromine Detailed Answer: There is no known direct interaction between duromine and levothyroxine, that is of clinical significance. This is to the best of my knowledge of published scientific literature. In general, levothyroxine should be taken with water on an empty stomach 30 to 60 minutes before breakfast. So it is advisable to take duromine and for that matter any other medications/tablets after this time gap. I see it has been 3 weeks since your thyroid surgery. When I see someone like you in my practice I typically run blood tests for thyroid function (TSH and Free T4) about 4 to 6 weeks after surgery to ensure appropriateness of the levothyroxine dose. It may require fine tuning for the first couple months to arrive at the dose appropriate for you. There is no direct conflict between the two medications. However, it would be reasonable to wait till levothyroxine dose is stable in the desired range, before duromine is introduced. The reason for this is that some of the effects and side effects of duromine (such as weight loss, rapid heart rate, high blood pressure, sleeplessness) can mimic those of excess levothyroxine doing. So if both are being taken together it can become difficult to distinguish between the impact of the two medications.