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Is IUI Safe In Presence Of HSV-2 Infection?

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Posted on Thu, 19 Mar 2015
Question: If someone infected with HSV2, and taking suppressive of Acyclovir 500mg a day therapy , can he do IUI to his partner for getting her pregnant without transmitting hsv2.
doctor
Answered by Dr. Sankaranantham Murugan (56 minutes later)
Brief Answer:
IUI is safe in presence of HSV 2 infection.Neonatal transmission unlikely

Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.

Very well IUI can be done to make his partner pregnant without transmitting HSV 2 infection.

1.Viral shedding would not be there always. It would be around the days of recurrence.
2. Virus usually not present in the body fluids like semen (unlike HIV), present in the Dorsal root nerve ganglions and periodically released along the nerve endings through skin and mucus membrane.
3. During the process of IUI, the semen is washed with appropriate fluids which can remove virus present, if any.
So it is safer to have IUI as a mode of conception in the presence of HSV 2 infection.
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Sankaranantham Murugan (40 hours later)
I recently got infected with HSV2 Take 1g of valacyclovir 2 times a day for 10 days. Dr Said I don't need of suppress therapy since most of the time you will never get the lesions back. If your wife get infection and get episode, treat her too. Nothing to worry , it is not life threatening. But I don't want to infect her I am planning to use the condoms all the time . My weight is 105Kg , How much dose of valacyclovir I have to take to limit my viral shedding and recurrence . Should I take it till I die or I can stop when my sexual activity goes to nil , will it not be bothering in my old age or in old age the recurrence does not happen ? Is there any alternative medicine for suppress thereapy
doctor
Answered by Dr. Sankaranantham Murugan (1 hour later)
Brief Answer:
Aciclovir and Famciclovir are the alternatives for valcyclovir

Detailed Answer:
Hi,
Welcome back.

Suppressive therapy usually recommended for 6- 12 months. Not life long. If necessary it can be repeated. Lifelong usage of condoms is not advised.

We can not predict the recurrence how long it will be active. It varies from person to person.
You asked for alternative drug for Valcyclovir. At the same time you wrote that you are on Acylovir suppressive therapy. Acyclovir and Famcylovir are the alternative drugs for Valcyclovir.
Dr S.Murugan
Note: Consult a Sexual Diseases Specialist online for further follow up- Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3109 Questions

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Is IUI Safe In Presence Of HSV-2 Infection?

Brief Answer: IUI is safe in presence of HSV 2 infection.Neonatal transmission unlikely Detailed Answer: Hi, Welcome to HCM. Thanks for posting your query. Very well IUI can be done to make his partner pregnant without transmitting HSV 2 infection. 1.Viral shedding would not be there always. It would be around the days of recurrence. 2. Virus usually not present in the body fluids like semen (unlike HIV), present in the Dorsal root nerve ganglions and periodically released along the nerve endings through skin and mucus membrane. 3. During the process of IUI, the semen is washed with appropriate fluids which can remove virus present, if any. So it is safer to have IUI as a mode of conception in the presence of HSV 2 infection. Dr S.Murugan