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Is Cymbalta Safe To Be Taken Post Heart Valve Replacement?

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Posted on Thu, 8 Dec 2016
Question: Hello ...
My mother is a XXXXXXX age 86... Had open pig valve replacement of main Aorta 5 years ago. Has since been plagued with depression and anxiety. She has been taking Remeron..?? For sleep/depression and sadly Xanax ( 1/2 of a .25 mg ) during the day for anxiety.
QUESTION: Is Cymbalta a safe replacement of the above mentioned medications.? According to certain information, Cymbalta could help with other aches and pains in the bones (arthritis / Bursitis) . Although I have just read in another search that Cymbalta has an effect upon "Cardiovascular":

Electrocardiogram Changes In Adult:
The effect of CYMBALTA 160 mg and 200 mg administered twice daily to steady state was evaluated in a randomized, double-blinded, two-way crossover study in 117 healthy female subjects. No QT interval prolongation was detected. CYMBALTA appears to be associated with concentration-dependent but not clinically meaningful QT shortening. ?!?

Also my mother has Otosclerosis... .Would you "RECOMMEND" Cymbalta to a patient like this...??? Per her doctor's 'guess' after Negative reactions with Prozac and Zoloft. Help..!

Cardiac Disorders — Frequent: palpitations; Infrequent: myocardial infarction and tachycardia.
Ear and Labyrinth Disorders — Frequent: vertigo; Infrequent: ear pain and tinnitus. HELP ..!!!
doctor
Answered by Dr. Prasanna Heijebu (13 hours later)
Brief Answer:
Cymbalta is not associated with such adverse effects

Detailed Answer:
Hello Madam

I can certainly understand your concern.

I have worked through your query in detail.

Cymbalta is not associated with any adverse effects on cardiac conduction or otosclerosis.

It has an excellent antidepressant effects.

Post your further questions if any.
Thank you,
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
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Dr. Prasanna Heijebu

General & Family Physician

Practicing since :2010

Answered : 1422 Questions

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Is Cymbalta Safe To Be Taken Post Heart Valve Replacement?

Brief Answer: Cymbalta is not associated with such adverse effects Detailed Answer: Hello Madam I can certainly understand your concern. I have worked through your query in detail. Cymbalta is not associated with any adverse effects on cardiac conduction or otosclerosis. It has an excellent antidepressant effects. Post your further questions if any. Thank you,