Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
193 Doctors are Online

I am a drinker. Having variations in liver enzymes. What is the risk I am facing?

User rating for this question
Very Good
Answered by

General & Family Physician
Practicing since : 2007
Answered : 353 Questions
My liver enzymes have gone up and Down over the years. I am quite a heavy drinker and at the moment they are six times normal. Are you able to help me quantify the risk I am facing and the long term diagnosis please
Posted Mon, 6 Aug 2012 in Smoking and Alcohol Addiction
Answered by Dr. Neelam Ashish Vanjari 1 hour later

Thanks for writing in.
To answer your question, the diagnosis is alcoholic liver disease. If you do not have any symptoms (like nausea, fever, jaundice, confusion, altered sleep pattern or any bleeding) at present, we may be looking at the earlier stages of alcoholic hepatitis. On the long term, we do expect it to proceed to severe alcoholic hepatitis and alcoholic cirrhosis finally.
The early stages of alcoholic hepatitis is not something very serious and the short term mortality is negligible. But over the long term, as the disease progresses, we could be looking at a 30 day mortality of 15-50%.
To exactly quantify the risk, we would need your prothrombin time and your bilirubin levels. With these results in hand, we can calculate a value called the discriminant function (DF). It is calculated as follows:
DF = (4.6 × PT prolongation) + total serum bilirubin in mg/dL
Values greater than 32 indicate severe disease and predict a 30-day mortality rate of approximately 50%, assuming only supportive treatment is given.
At this stage, the important thing to understand is that the disease is reversible. This however requires you to completely stop alcohol. With time still in our hands, we can give the liver enough time to take care of itself. But with continued use of alcohol, we can reasonably expect only a downhill course.
Do take the first step forward and try and reduce the alcohol you’re consuming.
I hope I have addressed your concerns.
Let me know if you need any more information.
Best regards,
Dr. Neelam.
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Medical Topics

The user accepted the expert's answer

Ask an Addiction Med Specialist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor