Question: I am a 49 year female with hypo enhancement on both sides of my pituitary gland, radiology report was inconclusive as to whether it was an adenoma.Two years ago my prolactin was elevated and I was treated with bromocryptin. This stopped me from producing breast milk but I have been on a roll coaster for two years. I have chronically low TSH, my endo. diagnosed me as hypopituitary.I also have anti-phospholipid syndrome my Mother has scerlroderma and my maternal Grandmother had hashimotos. I have also tested slightly low IGF-1. I am extremely fatigued, have had 9 sinus infections in last year and am currently on a 21 day regimen of Vioxx along with my Synthyroid 125 mcg. I have lost physical strength, normally I am a "gym rat" and former triathlete. I also have gained some weight and have not eaten any grains since last May, yet my weight will not drop. I feel on the verge of tears, yet I have no external problems in my life. I attempted to book an appointment with my Endo. and discovered he moved out of state. The physician taking over his patient load cannot see me until November 20. I need some answers sooner, in particular what are the BEST tests to determine GH deficiency, the medical literature is not in agreement as to what tests are the best.