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How Much Ferrous Gluconate Equals 325 Mg Of Ferrous Sulfate?

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Posted on Mon, 30 Jun 2014
Question: How much ferrous gluconate equals 325 mg ferrous sulfate?

ferrous sulfate causes severe constipation , cramps and gas I used to take ferrous gluconate but now they say because I am on Peritoneal dialysis I must take the fe sulfate I just don't believe it!
doctor
Answered by Dr. Shafi Ullah Khan (1 hour later)
Brief Answer:
Do as directed by doctor,

Detailed Answer:
Thank you for asking!
Your doctors are right.Peritoneal dialysis is not advised to be accompanied by gluconates as it may decrease the electrolytes too much like potassium leading to severe reactive hypokalemia ( decreased potassium).
As far as the adverse effects, gluconate or the sulfate has least to do with it. Its the ferrous form of iron which is criminal and notorious for such troubles.
Taking Iron polymaltose complexes are better if the ferrous supplements are non tolerable and i personally prefer iron Polymaltose complexes.
Rest taking the medicine on empty stomach with vitamin C helps the symptoms to reduce.
If the oral adverse effects are non tolerable try some recent advanced parenteral iron therapies like Ferumoxytol they have shown promising effects and work like charm.
Now the how much equivalence is simple. what ever the preparation is available is available over the counter in market is equivalent.
325 mg of ferrous sulphate has elemental iron of 65 mg and 325 mg of ferrous gluconate is 35 mg. so ferrous sulfate is twice the iron than in ferrous gluconate. But its the bioavailability that matters that is the percentage of iron that reaches the body for consumption which is higher for gluconate than sulfate by 20 % on average.
In nutshell, Do as directed by your doctor. You are in safer hands and you have nothing to lose and nothing to worry about.
Take good care of yourself and don't forget to close the discussion please.
May the odds be ever in your favour.
Regards
S Khan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shafi Ullah Khan (13 minutes later)
Thank you Dr XXXXXXX That was more info than I have received yet! So I'll forward his to my nephrologist Dr Konstentin Abramov who practices at UMASS Late Ave in XXXXXXX MA. He has taken great care of me but I really do not like the side effects of FeS. So your info may be very helpful!

Thanks again!

sincerely,

XXXX
doctor
Answered by Dr. Shafi Ullah Khan (3 minutes later)
Brief Answer:
:)

Detailed Answer:
You are welcomed Miss Marengo!
It was a pleasure to help you. If you need me you know how to find me.Don't forget to close the discussion please.
Regards
S Khan
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Shafi Ullah Khan

General & Family Physician

Practicing since :2012

Answered : 3613 Questions

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How Much Ferrous Gluconate Equals 325 Mg Of Ferrous Sulfate?

Brief Answer: Do as directed by doctor, Detailed Answer: Thank you for asking! Your doctors are right.Peritoneal dialysis is not advised to be accompanied by gluconates as it may decrease the electrolytes too much like potassium leading to severe reactive hypokalemia ( decreased potassium). As far as the adverse effects, gluconate or the sulfate has least to do with it. Its the ferrous form of iron which is criminal and notorious for such troubles. Taking Iron polymaltose complexes are better if the ferrous supplements are non tolerable and i personally prefer iron Polymaltose complexes. Rest taking the medicine on empty stomach with vitamin C helps the symptoms to reduce. If the oral adverse effects are non tolerable try some recent advanced parenteral iron therapies like Ferumoxytol they have shown promising effects and work like charm. Now the how much equivalence is simple. what ever the preparation is available is available over the counter in market is equivalent. 325 mg of ferrous sulphate has elemental iron of 65 mg and 325 mg of ferrous gluconate is 35 mg. so ferrous sulfate is twice the iron than in ferrous gluconate. But its the bioavailability that matters that is the percentage of iron that reaches the body for consumption which is higher for gluconate than sulfate by 20 % on average. In nutshell, Do as directed by your doctor. You are in safer hands and you have nothing to lose and nothing to worry about. Take good care of yourself and don't forget to close the discussion please. May the odds be ever in your favour. Regards S Khan