Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
132 Doctors are Online

How long it takes for the drug to be effectively eliminated from the body after administration of a single dose?

User rating for this question
Answered by

Internal Medicine Specialist
Practicing since : 2007
Answered : 362 Questions
I have a question....

If a drug has a half life of 6 hours, how long will it take for the drug to be effectively eliminated from the body after administration of a single dose?
Posted Sat, 4 Aug 2012 in General Health
Answered by Dr. Kiran Kumar 8 hours later

Thanks for writing in.

It usually takes Five Half Lives for a drug to be cleared from the body.

Eliminatin half life of the drug however is a dependent variable.
It depends on two factors.

1. Clearance. Most drugs are excreted by kidneys and therefore a normal kidney function is required to eliminate the drugs in five half lives. If there is derangement of kidney functions, the drug can be in the body for longer periods.

2. Volume of distribution. Some drugs are removed from the plasma or blod and distributed to other body fluids. From there, they are gradually liberated into the blood again. Here again, the elimination half life becomes prolonged.

If a steady state has been reached, a drug with half life of 6 hours would take 30 ie. 6 x 5, hours to be elimiated.

Hope this answers your query.

Do get back if you have any further concens.


Dr Kiran
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to

The user accepted the expert's answer

Ask a Doctor Now

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor