Brief Answer: PCOS Detailed Answer: Aldactone is also a diuretic ie a water pill in addition to having 'anti-androgen' effects meaning it opposes the effects of the male hormones in the body. Owing to the fact that it causes water loss it may provide some relief to individuals who tend to retain water for various reasons (Congestive heart failure, for example). In such persons, it does have a weight loss effect. In relatively healthy individuals like yourself, it does not normally cause weight loss. But I understand that you seem to be experiencing weight gain when you go off it, despite eating healthy. And this is of significant concern to you. In women considering pregnancy, it is important to go off aldactone anyway. Metformin, on the other hand, has the potential to result in 2% weight loss. The commonly prescribed dose of metformin is upto 2000 mg per day. So I suggest you consider discussing an increase in the metformin dose with your doctor.

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Brief Answer: Aldactone Detailed Answer: Aldactone blocks the effect of 'androgens' (male hormones) on the receptor of cells. If you wish to go off it, then you may want to try alternatives to reduce the excessive hair growth such as estrogen or eflnornithine. However, you must consult an endocrinologist in person before you consider these options.

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