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Have Taken Duo HIV Test, Came Negative. How Accurate Is This Test?

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Posted on Wed, 3 Oct 2012
Question: I took a Duo Hiv test at 70 days and it has come back as negtive, how accurate is this?
doctor
Answered by Dr. Jasvinder Singh (2 hours later)
Hello,
Thanks for posting your query.

The DUO test is an HIV test that looks for antibodies for HIV-1 and HIV-2 and also looks for evidence of the p24 protein which is on the surface of the HIV virus particle. p24 is only detected for a short time after infection, and before HIV antibodies can be detected.

A study found that the test was 100% accurate if you get a negative result, and 94% accurate if you get a positive result. A negative result would only need to be confirmed with a second test if you were exposed less than 3 months ago.

However Western Blot test is quite confirmatory for HIV. Western Blot HIV tests usually look for antibodies against the following HIV proteins:

•     Proteins from the HIV envelope: gp41, and gp120/gp160.
•     Proteins from the core of the virus: p17, p24, p55
•     Enzymes that HIV uses in the process of infection: p31, p51, p66
In order for a person to be considered HIV positive, they generally need to have either antibodies against one of the envelope proteins and one of the core proteins, or against one of the enzymes.

So you can get a western blot test done.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Please accept my answer in case you have no follow up query.

Wishing you good health.









Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Jasvinder Singh (25 hours later)
As my result was negtive at 70 days what is the chance of it changing at the 3 month stage to postive.

Thanks

XXXXXXX
doctor
Answered by Dr. Jasvinder Singh (13 hours later)
Hello,

Thanks for writing back to me.

Chances of duo HIV test coming positive after 90 days when it has come negative at 70 days with duo HIV test are very less likely. However it is better to get western blot done to be 100 % sure.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Please accept my answer in case you have no follow up query.

Wishing you good health.
Note: Get personalized answers to your HIV related queries You can choose to talk face to face with your doctor. Book a Video Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Jasvinder Singh

Internal Medicine Specialist

Practicing since :1998

Answered : 1578 Questions

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Have Taken Duo HIV Test, Came Negative. How Accurate Is This Test?

Hello,
Thanks for posting your query.

The DUO test is an HIV test that looks for antibodies for HIV-1 and HIV-2 and also looks for evidence of the p24 protein which is on the surface of the HIV virus particle. p24 is only detected for a short time after infection, and before HIV antibodies can be detected.

A study found that the test was 100% accurate if you get a negative result, and 94% accurate if you get a positive result. A negative result would only need to be confirmed with a second test if you were exposed less than 3 months ago.

However Western Blot test is quite confirmatory for HIV. Western Blot HIV tests usually look for antibodies against the following HIV proteins:

•     Proteins from the HIV envelope: gp41, and gp120/gp160.
•     Proteins from the core of the virus: p17, p24, p55
•     Enzymes that HIV uses in the process of infection: p31, p51, p66
In order for a person to be considered HIV positive, they generally need to have either antibodies against one of the envelope proteins and one of the core proteins, or against one of the enzymes.

So you can get a western blot test done.

Hope this answers your query. If you have additional questions or follow up queries then please do not hesitate in writing to us. I will be happy to answer your queries.

Please accept my answer in case you have no follow up query.

Wishing you good health.