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Have Degenerative Changes In Lumbar & Cervical Areas. MRI Showed Degree Of Heterogeneity In Marrow Signal Through Lumbar Region. Meaning?

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Posted on Thu, 24 Oct 2013
Question: nI am 62, have degenerative changes in lumbar & cervical areas. An MRI of lumbar findings stated the following: "There is a degree of heterogeneity in marrow signal through lumbar region, sacral and lower thoracic spine. This is nonspecific and maybe seen with relative hematopoietic marrow and/or possible degenerative/age related marrow changes. No acute compression fracture. No evidence of distinct infiltrative marrow replacement process"
This was ordered by a neurologist who never discussed the findings, as I was diagnosed with idiopathic polyneuropathy
What does it mean? Should I be concerned? I am mobile and do stretching exercises that seem to keep lumbar issues at bay so far. Do mild intensity exercise, so I am not incapacitated so far.
Thanks
XXXXX
doctor
Answered by Dr. K. Naga Ravi Prasad (1 hour later)
Brief Answer:
It means the bone marrow lacks uniformity.

Detailed Answer:
Hi, thanks for writing to XXXXXXX

Heterogeneity simply means that the bone marrow itself appears different that what normal bone marrow should look like on the MRI.

The heterogeneous means that there are areas which may appear to have changes in the bone marrow. For example, after injury or radiation to an area, the bone marrow can be replaced by fat causing the difference in appearance on the scan.

There are numerous causes for changes in the signal intensity in the marrow leading to heterogeneity which include Normal Variant of bone marrow, broken bones, Injury, Radiation, Bone marrow biopsies, Degenerative changes, Infection, Inflammation, Osteonecrosis and Bone tumours (myeloproliferative disorders) etc.

As you are not having any related symptomatology, your treating Neurophysician might have considered the findings as a Normal variant and might not have discussed anything about it. If you are concerned, discuss the issues with your treating physician.

Hope I have addressed your query.

Regards
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
Dr.
Dr. K. Naga Ravi Prasad

Orthopaedic Surgeon, Joint Replacement

Practicing since :1996

Answered : 2148 Questions

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Have Degenerative Changes In Lumbar & Cervical Areas. MRI Showed Degree Of Heterogeneity In Marrow Signal Through Lumbar Region. Meaning?

Brief Answer:
It means the bone marrow lacks uniformity.

Detailed Answer:
Hi, thanks for writing to XXXXXXX

Heterogeneity simply means that the bone marrow itself appears different that what normal bone marrow should look like on the MRI.

The heterogeneous means that there are areas which may appear to have changes in the bone marrow. For example, after injury or radiation to an area, the bone marrow can be replaced by fat causing the difference in appearance on the scan.

There are numerous causes for changes in the signal intensity in the marrow leading to heterogeneity which include Normal Variant of bone marrow, broken bones, Injury, Radiation, Bone marrow biopsies, Degenerative changes, Infection, Inflammation, Osteonecrosis and Bone tumours (myeloproliferative disorders) etc.

As you are not having any related symptomatology, your treating Neurophysician might have considered the findings as a Normal variant and might not have discussed anything about it. If you are concerned, discuss the issues with your treating physician.

Hope I have addressed your query.

Regards