HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Have Cirrhosis Of The Liver. Test Showed Decline In Albumin Level. Should I Be Concerned?

default
Posted on Thu, 17 Jan 2013
Question: My mom has cirrhosis of the liver hep c. Her recent blood test last week showed Albumin level 2.9. In August her Albumin level was 3.2. That is a big drop in a few months. She was diagnosed with cirrhosis 11 years ago.

What does the sudden decline of her Albumin mean?
doctor
Answered by Dr. Dinesh Kumar Singal (8 hours later)
Dear XXXXXXX,
Thanks for contacting XXXXXXX
Albumin is a indicator of synthetic function of liver. A drop in albumin over a period of time indicates progression of liver disease. Since your mother already has cirrhosis, probably it has progressed. Has HCV infection in your mother been treated with peg interferons? Treating HCV helps in stablising liver functions.
Hope my answer is useful to you.
You can get back to me if you have any further queries.
Best wishes.
Dr Dinesh Singal

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dinesh Kumar Singal (13 hours later)
Thank you for your reply.

Question: my mom's Afp-L3 result was 9.8. Is this high? Should We worry of possible liver cancer?

other info from results
protein 8.5
Afp fluctuates...52 to 162 to 79
doctor
Answered by Dr. Dinesh Kumar Singal (1 hour later)
Dear XXXXXXX,

Thanks for contacting again.

Her AFP is high but is not as high to consider liver cancer at this point of time. If it was more than 200 then possibility of liver cancer was high.

AFP-L3 fraction is a new test which measures AFP-L3 as a fraction of AFP. Patients with result more than 10% are more likely to develop liver cancer. In your mother's case it is 9.8% which is a borderline value, so she needs close monitoring and frequent follow-up for liver cancer.

Best wishes.

Dr Dinesh Singal
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dinesh Kumar Singal (21 hours later)
I was wondering ...

My mom's sodium and HDL are low all of a sudden.

sodium 133 low
Cholesterol, total 121 low
hDL cholesterol 39 low

1. Question...Should we be concern that she may have ascites?
2. Question...what do these results mean given she has cirrhosis?
doctor
Answered by Dr. Dinesh Kumar Singal (1 hour later)
Dear XXXXXXX,

Yes, she may have ascites. You need to get a sonological (ultrasound) examination to rule that out. Low sodium usually occurs in cirrhosis due to excess of water retention. This is why ascites also occurs in these patients.

Cholesterol levels go down in cirrhosis due to poor synthesis.

Dr Dinesh Singal

Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dinesh Kumar Singal

Gastroenterologist

Practicing since :1985

Answered : 140 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Have Cirrhosis Of The Liver. Test Showed Decline In Albumin Level. Should I Be Concerned?

Dear XXXXXXX,
Thanks for contacting XXXXXXX
Albumin is a indicator of synthetic function of liver. A drop in albumin over a period of time indicates progression of liver disease. Since your mother already has cirrhosis, probably it has progressed. Has HCV infection in your mother been treated with peg interferons? Treating HCV helps in stablising liver functions.
Hope my answer is useful to you.
You can get back to me if you have any further queries.
Best wishes.
Dr Dinesh Singal