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Have Chronic Nutropenia. Sister And Brother Diagnosed With Addison's Disease. Are The Conditions Related?

Posted on Sun, 4 Aug 2013

Question: Hello, I have chronic nutropenia, my brother died from addisons desease, an now my sisters son has been diognosed with addisons desease , ae these conditions related?

Answered by Dr. Vaishalee Punj (1 hour later)

Hi

Thanks for posting your query on XXXXXXX

I researched a lot on the correlation between two diseases - chronic neutropenia and Addison's disease.

I could not find any genetic correlation between them.

A correlation is possible in two other ways:

One is that an auto-immune disorder that is directing auto-antibodies towards your neutrophils and towards the adrenal glands of other family members. This possibility is remote. If the autoimmune disorder is present by birth then it will direct auto-antibodies to either the organs or the blood elements. If the auto-immune disorder is acquired then it will usually direct auto-antibodies to different tissues or organs and can produce a multitude of symptoms.

Second is that Addison's disease can cause neutropenia as a complication.

Let me know if you need further clarification.

Dr Vaishalee

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar