Brief Answer:
Get medical help for your penile lesions asap.

Detailed Answer:
Hello and thanks for your query.

I shall make an effort to provide you with good professional recommendations specific to your questions.Your history shows up immediate concerns and also long term concerns. Let me address all.

Firstly, the penile issues that you currently face and the Herpes history seem to be well correlated. I would treat such a case with a strong suspicion of Herpes infection before I can think of other Sexually Transmitted Diseases (STDs). The lesions you have described fit well into the definitions of a developing STD and should be confirmed by blood tests as soon as possible. Apart from Herpes which is the primary suspect, other coexisting STDs also will have to be done including most commonly occurring Syphilis, HIV amongst others.

Secondly, the antibiotics (which you have not mentioned the brands) are very specific and there is rarely a need to change them unless the diagnosis is drastically different. Anti-viral drugs for set duration and dose will be decided beforehand. Urine sample is not to be correlated with this antiviral drug efficacy against Herpes infection. If you write in the names - I can better guide you with a comprehensive answer regarding the options available for you now.

Next, having unprotected sex like in your past is never advisable. Since, all STDs spread to the partner. And now, your partner also needs treatment for the same as you would have to undergo after similar blood tests for a STD screening like in your case.

Lastly, your enlarged prostate may not be of immediate concern but would need regular checks with blood antigen tests that make sure cancer development is not taking place. Your hypertension may have a definite association with this prostate enlargement but with the right drugs (you have not mentioned your antihypertensive medications) the enlargement may also be controlled along with good control of blood pressure.

The possibility of drug resistance will arise if your antibiotics have been prescribed by a doctor, for the right indication and then switched over to another. But, in this case a higher antibiotic is carefully prescribed in order to work depending on the sensitivity reports.

Let me know if I have missed out any other concern in your question.

Yet again, I duly appreciate your query to me, I do hope that you have found something useful to help you and I shall be glad to answer any further apprehensions.

Sincerely,

Dr Sujeet N Charugulla,
MBBS, MD.
Consultant Physician.

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