Have Back Problem. MRI Showed Abnormally Low Bone Marrow Signal Diffusely At All Levels. What Does This Mean?
Thanks for posting your query.
I have read the details submitted with diligence. The MRI findings reported concerns me.
Abnormal bone marrow signal are associated with either metastatic disease from solid primary tumour or hematological disorders like leukemia, lymphoma or multiple myeloma.
- Metastatic disease from solid primary malignancy show focal pattern consisting of localized area of abnormal marrow.
- While leukemia reveal a diffuse pattern of abnormal marrow on MRI.
You will need further tests consisting of blood test and plasma cell profile in consultation with a competent hematologist to rule out hematological disorders. Please consult the referred doctor or a competent hematologist back at home.
Let me know if you have more concerns, I will be please to help you.
Good luck!!!
Thanks for posting your query again.
Physiologic demand for more mature blood cells (especially red blood cells) beyond the body's normal capacity to produce them acts to reverse the normal pattern of conversion of red marrow to yellow marrow. This stimulated growth of hematopoietically active marrow increases the visibility of red marrow in the axial and appendicular skeleton. This process is referred to as reconversion .
This increase physiological demand for red blood cells is might be due to anemia in your case.
Hope I have answered your query. Let me know if you have any more concerns.
Wishing you good health.
Regards.
Answered by
Dr. Saurabh Gupta
Orthopaedic Surgeon, Joint Replacement
Practicing since :2004
Answered : 5930 Questions