Brief Answer: Yes, can be normal; please do not increase dose Detailed Answer: Hello sir and welcome. Thank you for writing to us, Yes sir, 150 mg of wellbutrin can have an effect lasting from about 2-4 days, varying from person to person, so this would be considered normal. Also in your case, as you have just started on the medication it may take sometime till the effect of the medication becomes constant, so please be patient. As for doubling the dosage, this would not be considered safe unless your prescribing doctor thinks it necessary, and would take the utmost care in ensuring your safety, as overdoses can result in seizures. In my opinion, you can wait for a few days sir (3-5 days), and if the effect of the medication does not become constant, then please contact your doctor and see if he can either increase the dosage or substitute it with another medication. I hope you find my response helpful sir. Please feel free to write back to me for any further clarifications, I would be more than happy to help you. Wishing you nothing but good health. God bless.

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