Brief Answer: No, estrogens do not cause constipation! Detailed Answer: Hi and thank you so much for this query. I am so sorry to hear about what your mom has been experiencing. Estrogen replacement does not in any ways cause constipation. Also, may I ask why she has been using this drug for such a longtime despite the fact that it is often being recommended for short term use to relief symptoms. Because she has seen many doctors and has done tests with no abnormality discovered, I think this could represent functional colopathy. This is a condition in which a patient presents with symptoms that are not explained by any identifiable diseases or disease condition. This is manged by taking care of the symptoms so as to improve the quality of life of the patient. in the case of constipation, we recommend increase fiber intake, increased fruits, vegetables and fruits alongside increased fluids consumption. also, staying physically fit would help relief some of these symptoms. If these life style modifications should fail to ameliorate this condition, then periodic laxatives can be used to help improve her bowel movements. Insomnia can be managed with sleep aid and also a good sleep hygiene. Avoiding to sleep on the bed when not sleeping time, reducing distractions when in bed, avoid excessive daytime naps, etc. This helps to ameliorate the amount and quality of sleep. Please talk with one of her doctors to consider getting her on one of these medications if need be. I hope you find this condition helpful. I wish her he best of possible outcomes. Thank you for using our services and please do feel free to ask for clarifications if need be. Dr. Ditah, MD

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