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Done Test For Infertility, Semen Analysis Normal. Is Histopathological Endometrium Examination Due To Increased Lymphocyte The Correct Process?

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Posted on Fri, 7 Sep 2012
Question: i am undergoing infertility checks...i m female, 27 yrs
below are the test done:
1)montoux=>+ve
2)chest x-ray=>normal
3) Haemogram=> (erythrocyte count-5.28 mill/cumm,haemogram-11.5,PCV-35,MCV-66.3,MCH-21.7,MCHC-32.8,RDW-16.3,Leucocytes count-5100 /cumm,neutrophils-46%,eosinophils-1,lymphocytes-49%,monocytes-4,basophils-0, platelet count-206)
4)hormones(3rd day of cycle)=> glucose fasing-81,fsh-9.01,lh-7.45,prolactin,serum-7.26

my husband's semen analysis normal(only actively motile-30%,sluggish motile-40%, non-motile-30%,vol.-5.0 ml,pus cell-2-3,liquification-35 min, color-pearly white,pH-Alakaline, sperm count-86 milln/ml)
before haemogram test my HSG was due but after tht my doctor said now she will do histopathological endometruim examination(due to increased lymphocyte)...could you please advice is this correct process and how lymphoctes effect hsg process??
doctor
Answered by Dr. Mahesh Koregol (6 hours later)
Hi XXXXXXX,

Thanks for your query.

Among above investigations you have mentioned, you have positive mantoux test (Tuberculosis).But leucocyte count is not so high.

Following are my advice and comments:

1) Mantoux test positive indicates tuberculosis (TB). Genital tract TB is a worst infection which causes infertility. Mantoux detects TB in your body but not exactly which part of body.

2) Generally 2 out of 10 women suffering from TB are infertile. More than 50 % of women with infertility have TB.

3) When your gynecologist wants to do a histopathological exmination, she might wanted to check for tuberculosis which is correct method.

4) Please request your gynecologist to do following investigations with your D&C sample: 1. Histopathology 2. PCR(Polymerase chain reaction) for TB mRNA 3) Culture of endometrial tissue for TB.

5) If your examination turns out to be positive for TB you may have to take 6 month treatmment for TB which is necessary and important.

I hope I answered your questions. I will be available for any followup queries you have. If no more queries, please accept my answer and close this discussion.

Regards,
Dr.Mahesh Koregol
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Mahesh Koregol (4 hours later)
Thanks for the response doctor :)
my doctor prescribed ADDYZOA and Norflox-400 for sperm motility for 1 months...noflox is a antibiotic..is taking 2 antibiotic a day is safe for body? Is he really required medicine? if yes, kindly suggest some good medicine without or min. side effect..thanx
doctor
Answered by Dr. Mahesh Koregol (9 minutes later)
Hi, thanks for writing.

Your husband actually need not take any medications as everything is normal. The motility is not significantly low. I don’t recommend taking any medication. Especially antibiotic should not be taken for one month. I see no necessity to take medications.

Hope I answered all your questions. If you do not have any more queries, please close this discussion.

Regards,
Above answer was peer-reviewed by : Dr. Shanthi.E
doctor
Answered by
Dr.
Dr. Mahesh Koregol

Infertility Specialist

Practicing since :2000

Answered : 3830 Questions

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Done Test For Infertility, Semen Analysis Normal. Is Histopathological Endometrium Examination Due To Increased Lymphocyte The Correct Process?

Hi XXXXXXX,

Thanks for your query.

Among above investigations you have mentioned, you have positive mantoux test (Tuberculosis).But leucocyte count is not so high.

Following are my advice and comments:

1) Mantoux test positive indicates tuberculosis (TB). Genital tract TB is a worst infection which causes infertility. Mantoux detects TB in your body but not exactly which part of body.

2) Generally 2 out of 10 women suffering from TB are infertile. More than 50 % of women with infertility have TB.

3) When your gynecologist wants to do a histopathological exmination, she might wanted to check for tuberculosis which is correct method.

4) Please request your gynecologist to do following investigations with your D&C sample: 1. Histopathology 2. PCR(Polymerase chain reaction) for TB mRNA 3) Culture of endometrial tissue for TB.

5) If your examination turns out to be positive for TB you may have to take 6 month treatmment for TB which is necessary and important.

I hope I answered your questions. I will be available for any followup queries you have. If no more queries, please accept my answer and close this discussion.

Regards,
Dr.Mahesh Koregol