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Does A Negative DNA PCR Result Rule Out HIV-1 Infection?

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Posted on Tue, 2 Feb 2016
Question: I took a pcr dna hiv test that came back not detected 8 weeks ago do i need to take an hiv antibody test also to confirm my hiv negative status?
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Answered by Dr. Sankaranantham Murugan (27 minutes later)
Brief Answer:
Negative DNA PCR rule out HIV 1 infection

Detailed Answer:
Hi, Welcome to HCM
Thanks for posting your query.
How long after the exposure, you had your PCR test? If it is after 3-4 weeks, then it can be taken as conclusive. The negative test ruled out the possibility of HIV 1 infection. To rule out HIV 2 infection, you have to take up an antibody detection test after the window period.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Sankaranantham Murugan (17 hours later)
Can i take a hiv antibody test 9 weeks after possible exposure and will it be conclusive
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Answered by Dr. Sankaranantham Murugan (5 hours later)
Brief Answer:
Highly reliable by 9 weeks. Comfirmatory after 12 weeks.

Detailed Answer:
Hi,
Welcome back.
HIV Antibdy test by 9 weeks is highly reliable as it crossed the window period. But can be considered more conclusive by 12 weeks as the antibody formation against HIV in the presence of an infection could be delayed in some individuals. If you don't mind, you can repeat the test once agin after 12 weeks to get a more confirmed result.
Dr S.Murugan
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Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
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Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3110 Questions

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Does A Negative DNA PCR Result Rule Out HIV-1 Infection?

Brief Answer: Negative DNA PCR rule out HIV 1 infection Detailed Answer: Hi, Welcome to HCM Thanks for posting your query. How long after the exposure, you had your PCR test? If it is after 3-4 weeks, then it can be taken as conclusive. The negative test ruled out the possibility of HIV 1 infection. To rule out HIV 2 infection, you have to take up an antibody detection test after the window period.