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Does Mycobacterium Infection Cause Miscarriage?

Posted on Thu, 2 Apr 2015

Question: Hi doc, i have had kind of mis carraige a month ago, why i mentioned kind of is thst wasnt exactly mis carraige., baby wasnt taking flows from mother since month hence was v weak, after delivery we sent chord for test..in test mycobacterium tuberclosis was confirmed in endometrium (uterus) what is procedure now..how to go about it.will it be cured Permanently? ..will next baby be a problem? Who is best doctor in XXXXXXX / ncr Pls guide us in detail...

Answered by Dr. Mahesh Koregol (46 minutes later)

Brief Answer:
Please provide details

Detailed Answer:
Hi,

Thanks for your query.

I read your query and I understand your concerns about miscarriage.

I need following details before answering your question:

1) Miscarriage was unfortunate. What was the period of gestation. when was your last period date?

2) How was tuberculosis diagnosed ? Culture or PCR test ?

3) Please scan and attach the discharge copy from hospital after miscarriage.

I hope I answered your query. I will be available for any follow up query you have.

Regards,
Dr. Mahesh Koregol
IVF & Infertility Specialist

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mahesh Koregol (22 minutes later)

hi doc,
Last period date: 15th july 2014
Mis carriage date: 15th february 2015
Tuberclosis was diagnosed by pcr test
Unable to scan image here..there isnt any option..however mentioning main points:
Diagnosis: prumi c imath anim, severe IUGR, severe oligoamnios, reversed doppler flow, devilery at 30 weeks
Operation notes: delivered dead male feutus.. placental tube sent for pcr & genetic study

Answered by Dr. Mahesh Koregol (11 minutes later)

Brief Answer:
Tuberculosis is unlikely to be the reason

Detailed Answer:
Hi,

TB may not be reason for preterm, IUGR baby.

Many times PCR report is wrong. I think we should wait for genetic report.

Were you hypertensive or diabetic?

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Mahesh Koregol (9 hours later)

Genetic report is normal.
cytogenetoc profile:
Autosomes: 44
Sex chromosome number: 2
Ttl chromosome nmbr: 46
Translocation / inversion / deletion : nil
Feutus has normal cytogenetic profile with no chromosomal abnormalities detected.
Im not hertensive or diabetic
Please guide doc, should we contact gynae in medaanta or tb specialist.

Answered by Dr. Mahesh Koregol (7 hours later)

Brief Answer:
This is unlikely to be TB

Detailed Answer:
HI,

This does not seem to be tuberculosis. TB cannot be reason for such IUGR. In light of normal chromosomal parameters and IUGR it is difficult to explain.

I would suggest following line of management:

1) First see TB specialist and get tuberculosis diagnosis done by other methods like culture. PCR may be false positive.

2) If culture shows positive, start treatment for TB.

3) After this see a gynecologist. In XXXXXXX you can see Dr. XXXXXXX XXXXXXX who is good at such work. Her number is 0000. Please tell her Dr. Mahesh from XXXXXXX reffered you.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar