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Does Hydroxyzine Pamoate Interact With Diphenhydramine?

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Posted on Thu, 19 Nov 2015
Question: Is it safe to take a Hydroxyzine Pamoate (25 MG) with the 2- 25MG Diphenhydramine I recently took?
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Answered by Dr. Ivo Ditah (29 minutes later)
Brief Answer:
THis is not advised!

Detailed Answer:
Hi and thank you so much for this query.

I am so sorry to hear about this supposed food allergy. Unfortunately, these drugs are exactly the same and I will not advise that you take both. This is because they both cause sedation and can cause severe sedation when taken together. If the itches are too severe, I will rather recommend you use prednisone/bethamethasone which is a steroid and good in cases of body itches.

I hope this helps. I wish you well and thanks for using our services. Feel free to ask for more information and clarifications if need be.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ivo Ditah

Internal Medicine Specialist

Practicing since :2002

Answered : 3984 Questions

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Does Hydroxyzine Pamoate Interact With Diphenhydramine?

Brief Answer: THis is not advised! Detailed Answer: Hi and thank you so much for this query. I am so sorry to hear about this supposed food allergy. Unfortunately, these drugs are exactly the same and I will not advise that you take both. This is because they both cause sedation and can cause severe sedation when taken together. If the itches are too severe, I will rather recommend you use prednisone/bethamethasone which is a steroid and good in cases of body itches. I hope this helps. I wish you well and thanks for using our services. Feel free to ask for more information and clarifications if need be.