Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
179 Doctors are Online

Does Depakote ER have any side effect on pregnancy ?

User rating for this question
Very Good
Answered by
Practicing since : 1983
Answered : 979 Questions
Question
I am five and a half weeks pregnant (LMP 6/2/11). I was 750 mg of Depakote ER up until 7/6/11. What are the chances my baby has a birth defect? I realize that the neural tube forms around 4 weeks, which was when I stopped taking the medication. I am very worried about the child, and am considering terminating the pregnancy because of the exposure to the Depakote.
Posted Sat, 21 Apr 2012 in Medicines and Side Effects
 
 
Answered by Dr. Minoo Bhagia 9 hours later
Hello,

Thanks for your query.

Valproic acid is folate antagonist and known to cause neural tube defects like spina bifida.

Organogenesis starts just after implantation that is one week after fertilization (1-3 weeks).
Birth defects are possible. The chances are less though.

I suggest that you get ultrasound scan between 8th to 12th week which will diagnose birth defects. You may consider termination if scan reveal birth defects.

Hope I have answered your query. Should you have any more concerns, I will be available for follow ups.

Regards
Above answer was peer-reviewed by
 
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Drug/Medication
Medical Topics

The user accepted the expert's answer

Ask an Internal Med Specialist

©2014 Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions