Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
183 Doctors are Online

Do twenty atypical moles or twenty moles be an indication of FAMM? Does the severity matter in terms of risk of melanoma?

User rating for this question
Answered by

Practicing since : 1980
Answered : 254 Questions

I think I heard my dermatologist say if someone has 20 atyplical moles on each forearm, that could be an indication of FAMM. But, I am not sure if he said 20 atypical moles or 20 moles. Do you know?
Also, does the severity of the atypical matter in terms of potential risk for future melanoma?

Posted Mon, 21 May 2012 in Skin Cancer
Answered by Dr. P V S Prasad 8 hours later

I went through your history. Familial atypical mole or melanoma (FAMM) syndrome includes positive family history of melanomas or a tendency to develop multiple dysplastic nevi. Dysplastic nevi mean atypical moles. They are large pigmented lesions size measuring from 5 to 10 mm in diameter and they show irregular borders or ill defined.
Atypical moles may appear anywhere.

In FAMM syndrome the lesions should be more than 100 altogether.

A biopsy should be done to confirm atypical moles.

I hope I clarified your doubts.

Good day.

Prasad pvs

Above answer was peer-reviewed by
Follow-up: Do twenty atypical moles or twenty moles be an indication of FAMM? Does the severity matter in terms of risk of melanoma? 13 hours later
Thank you for your response.
Is that 100 atypical moles or just 100 moles?
I do not have anyone in my family with melanoma. I have had 5 mildly atypical moles.

I have been to two dermatologist that do not see anything else of concern.
However, as I begin to look at my moles, I feel they are all weird. I probably have about 20 or less moles over my entire body. None are larger than 1-2 mm. But, I worry that some could be atypical. If they were all atypical that could put me in the FAMM risk area is that right?
Answered by Dr. P V S Prasad 16 hours later
Thanks for writing back.
To put you into the category for FAMM, the number of moles should be more than 100. These are just normal moles and not necessary atypical moles. If you do not have any family history of this condition, the chances of you having it are remote.
The following changes in a mole can be possibly indicative of a malignancy:
a.     Atypical changes
b.     Enlarging borders
c.     Rough contours
d.     A diameter of >1.5 cm
Further, if these changes are present, a skin biopsy needs to be done to make a diagnosis of a malignancy.
I would like to reassure you that you do not need to worry at present. I suggest that you have an annual check up to rule out dysplastic ( changes possibly suggestive of malignancy) changes in the moles.
I hope I have addressed your concerns.
Above answer was peer-reviewed by
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
Lab Tests

The user accepted the expert's answer

Ask an Oncologist

© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor