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Diagnosed With Kebesella Oxycoat Infection. Is Faropenem Better Than Imepenem?

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Posted on Mon, 6 May 2013
Question: my sister has been diagonised with kebesella oxycoat infection.she been with it for one and half years . she was given , amikacin gentamicin taobactum and lastlly imepenem.now for the last 3 months she is been prescribed faropenem tablets . is faropenem better than imepenem , are they one and the same thing.
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Answered by Dr. Achuo Ascensius (4 hours later)
Hello,
thanks for the query.

I appreciate the history you have given for it is very relevant.
It is unfortunate that your sister's diagnosis was only made at a later stage but however, the essential thing is that the diagnosis was finally made from which there is a way forward.

Klebsiella infections are typically resistant infections and most often occurring with multiple drug resistance. This is usually overcome by doing an antibiogram to determine the range of antibiotics to which the germ is sensitive to. Empiric treatment however would target gram negative since Klebsiella oxycota is a gram negative bacteria. Gentamycin, amikacin, tobramycin and impenem all are effective against gram negative bacteria which do not have any resistance so far.
Faropenem and imipenem all belong to the same group of antibiotics known as penems. Faropenem is relatively new and is a modification of imipenem, thus more stable and more active against enzymes produced by bacteria.
An effective way of getting the right drug will be to do an antibiogram to test the sensitivity of various antibiotics and see which will be most effective.

Hope this answers your query. If you have more query, do not hesitate and if you do not have further query, you could close the discussion and rate the answer.
Wishing your sister a speedy recovery.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Achuo Ascensius

General & Family Physician

Practicing since :2012

Answered : 1040 Questions

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Diagnosed With Kebesella Oxycoat Infection. Is Faropenem Better Than Imepenem?

Hello,
thanks for the query.

I appreciate the history you have given for it is very relevant.
It is unfortunate that your sister's diagnosis was only made at a later stage but however, the essential thing is that the diagnosis was finally made from which there is a way forward.

Klebsiella infections are typically resistant infections and most often occurring with multiple drug resistance. This is usually overcome by doing an antibiogram to determine the range of antibiotics to which the germ is sensitive to. Empiric treatment however would target gram negative since Klebsiella oxycota is a gram negative bacteria. Gentamycin, amikacin, tobramycin and impenem all are effective against gram negative bacteria which do not have any resistance so far.
Faropenem and imipenem all belong to the same group of antibiotics known as penems. Faropenem is relatively new and is a modification of imipenem, thus more stable and more active against enzymes produced by bacteria.
An effective way of getting the right drug will be to do an antibiogram to test the sensitivity of various antibiotics and see which will be most effective.

Hope this answers your query. If you have more query, do not hesitate and if you do not have further query, you could close the discussion and rate the answer.
Wishing your sister a speedy recovery.