Question: I have spent the last 5-6 mos. reducing fentanyl patch from 20+yrs use-i've gone from 100 mcg/hr every 3 days to current 12 mcg/her every 3 days. I have experienced w/drawl from anxiety, depression, and "electrical shocks" that cause the need to shake my arms and legs so hard I end up sleepless-as I have reduced the dose the third day and more severe at night as I draw near to morning and replacing a new patch-my symptoms are now my legs have that electric shock that is in my mind more like restless leg. I begin as I lay in bed prior to trying to sleep. I have begun to have leg cramps running the length and feet and toes. I have trazodone 100mg 1 tab at night for over 20 yrs. My dr ( visited 9/6) stopped them to help shakes- only 5dys in no relief. She said to add magnesium and K along w/ my C+ and D- now cramps are "rippling" down leg muscles. I take gabapentin, methocarbenal, 2 unisom, 2 dyphenhydramine ( do not cause sleep or nervousness day or night ), and the above mentioned vitamins at night. I have acute fibromyalgia, stenosis, spondilitis, DDD, fusion L4L5, and scoliosis. Fusion in 2011. My left knee is arthritic w/ ortho stating to replace for 10 yrs. I do take a 5/350 Vicodin at night 3-5 x week. Also as of 9/6 started Lyrica 50mg 1/wk to now am/pm wk upping to 3x daily. I take paoxetine 60mg am daily. I've taken Lyrica before it lifted depression but caused 15 to 18 hrs. sleep! I would relish effect at this time! I decided to quit patches due to new XXXXXXX And the fact my life as far as travel etc. was always around that 30 day need to refill. Of course I am now dealing w/ my life draining chronic pain. I have osteoporosis taking raloxifene 60 mg 1/day am. Why the cramps and electric shocks in legs at night even on night 1 of patch? I do wear a knee brace days but not every day. My left leg is always swollen larger than right since surgery for large tumor (lymph node, cat scratch fever, dx external cause not CA) in 1963. 3 yrs. post leg swelled w/ spongy fluid 3x size. Pressing into leg at 1 to 2 inches by shoes or finger pressure. I was 12 yrs. no dr. As it slowly filtered away no pain during or after but leaving swelling at various levels. I do have varicose veins 2x than rt leg. Knee medial discus torn and surgery removal no repair of ligaments etc. age 16- " popping out" then on-I was athlete never the less knee preventing college sports. Ok back to this horrific spasms and cramps now- dr prescribed clonidine 0.1mg 9/6 visit does help relax a bit but only prescribed 10 tabs- so save for worse nights prior to new patch. Please help me-thank you.