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Can The Usage Of Lisinopril Cause Elevated Creatinine Levels?

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Posted on Mon, 20 Apr 2015
Question: I am taking 20 mg lisinopril daily for a slight elevation in BP. My creatinine is elevated. Value 2.13 with high level in range being 1.18 . Can my use of lisinopril 20 mg qd be causing this elevation in creatinine? If so, what ACE inhibitor would be a better choice that medicare would approve?
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Answered by Dr. Ronald Schubert (9 minutes later)
Brief Answer:
ACE inhibitors cause elevated creatinine

Detailed Answer:
Thanks for contacting HCM with your health care concerns

You are very right. ACE inhibitors will cause elevation in creatinine and also potassium levels. Once you have elevations due to an ACE then you need to be taken off the ACE and placed on different medications. I will usually switch people from an ACE to an ARB or angiotensin receptor blocker. these medications are second generation ACE that do not have the side effects and elevation problems seen with ACE. Names of ARBs are losartan, irebsartan and valsartan to name a few.

I recommend that you discuss this with your provider and see if you would be a candidate to switch to an ARB

I hope this answers your question. Please contact us again with any of your health care concerns or questions
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Ronald Schubert

General & Family Physician

Practicing since :1984

Answered : 2407 Questions

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Can The Usage Of Lisinopril Cause Elevated Creatinine Levels?

Brief Answer: ACE inhibitors cause elevated creatinine Detailed Answer: Thanks for contacting HCM with your health care concerns You are very right. ACE inhibitors will cause elevation in creatinine and also potassium levels. Once you have elevations due to an ACE then you need to be taken off the ACE and placed on different medications. I will usually switch people from an ACE to an ARB or angiotensin receptor blocker. these medications are second generation ACE that do not have the side effects and elevation problems seen with ACE. Names of ARBs are losartan, irebsartan and valsartan to name a few. I recommend that you discuss this with your provider and see if you would be a candidate to switch to an ARB I hope this answers your question. Please contact us again with any of your health care concerns or questions