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Can Positive Mono Igg And Igm Can Cause A False Positive Ra?

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Posted on Tue, 24 Dec 2013
Question: I was tired with swollen glands two years ago ..labs came back positive for mono. Igg and igm. Positive. Problem is i still have joint aches and intermittent swolllen glands. And two years later i am still positive for mono. I had another localized infection in my throat and was tested for cytomeglvirus and came back positive for this recently(igg and igm) . And again igm pos for mono. Last month i got bit by a tick and tested positive for lyme. But western blot was negative. I was concerned about being positive for so many virus and gor so long 2 years so idid an aids test and it was negative. Could something be causing me tohave false positives.? My symptoms are very!!! Very painful joints, sperfuse sweating and swallen glands.
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Answered by Dr. Dr. Shruti Rijhwani (10 hours later)
Brief Answer: Follows. Detailed Answer: Dear Sir, Thank you for posting your query on XXXXXXX Well looking into your problem I would like to tell you that once you have a viral infection then it is possible that you test falsely positive for other viruses even later. It will not be possible to comment upon the cause but I think you require a thorough evaluation . A physical examination , other tests pertaining to evaluation of arthritis like ESR , CRP , RF , Anti CCP , ANA will be necessary . Pattern of joint involvement needs to be seen . Rheumatoid arthritis like conditions also needs to be ruled out . If there is any skin rash also needs to be seen . Take care. Dr. Shruti
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Dr. Shruti Rijhwani (5 hours later)
I heard that positive mono igg and igm can cause a false positive ra . Is this true?
doctor
Answered by Dr. Dr. Shruti Rijhwani (21 hours later)
Brief Answer: Follows. Detailed Answer: Dear Sir, Thank you for reverting back. Well yes it is possible that Rheumatoid factor is a cause of positive reactions in tests for Epstein–Barr virus-specific IgM antibodies because RF itself is IgM antibody so cross reactivity is possible . Dr. Shruti
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Shruti Rijhwani

Rheumatologist

Practicing since :2008

Answered : 2366 Questions

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Can Positive Mono Igg And Igm Can Cause A False Positive Ra?

Brief Answer: Follows. Detailed Answer: Dear Sir, Thank you for posting your query on XXXXXXX Well looking into your problem I would like to tell you that once you have a viral infection then it is possible that you test falsely positive for other viruses even later. It will not be possible to comment upon the cause but I think you require a thorough evaluation . A physical examination , other tests pertaining to evaluation of arthritis like ESR , CRP , RF , Anti CCP , ANA will be necessary . Pattern of joint involvement needs to be seen . Rheumatoid arthritis like conditions also needs to be ruled out . If there is any skin rash also needs to be seen . Take care. Dr. Shruti